Estimation of endogenic intoxication laboratory indexes in case of different pathologies of professional and infectious etiology


DOI: https://dx.doi.org/10.18565/therapy.2021.9.174-182

Kuzmina L.P., Pilat T.L., Bezrukavnikova L.M., Kolyaskina M.M.

1) Academician N.F. Izmerov Scientific-research Institute of Occupational Medicine, Moscow; 2) I.M. Sechenov First Moscow State Medical University of the Ministry of Healthcare of Russia (Sechenov University)
Abstract. Endogenous intoxication in case of various pathologies of occupational and infectious etiology plays an essential role in the healing process and in estimation the severity of the disease. Specifying of endogenous intoxication indexes by means of biochemical markers use will help to control detoxification processes, including through the inclusion of various specialized foods in the complex therapy of dietary therapeutic and dietary preventive nutrition. Use of alimentary factors in the process of reducing the negative impact of toxic substances of endogenous origin at human organism should be aimed at maintaining and preserving the rhythm of the main homeostatic systems functioning. The aim of this review is to assess the informative content of endogenous intoxication indexes in various pathologies having occupational and infectious etiology.
Keywords: biochemical studies, therapeutic and prophylactic nutrition, detoxification, endogenous intoxication
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About the Autors

Lyudmila P. Kuzmina, doctor of biological sciences, professor, deputy director for research work of Academician N.F. Izmerov Scientific-research institute of Occupational Medicine, professor of the Department of occupational medicine, aviation, space and diving medicine, I.M. Sechenov First Moscow State Medical University of the Ministry of Healthcare of Russia (Sechenov University). Address: 105275, Moscow, 31 Budennogo Avenue. E-mail: lpkuzmina@mail.ru. ORCID: 0000-0003-3186-8024
Tatiana L. Pilat, MD, leading researcher of Academician N.F. Izmerov Scientific-research Institute of Occupational Medicine. Address: 105275, Moscow, 31 Budennogo Avenue. Tel.: +7 (495) 366-06-09; +7 (495) 663-35-96. E-mail: tpilat@leovit.ru. ORCID: 0000-0002-5930-8849
Lyudmila M. Bezrukavnikova, PhD, leading researcher of the Laboratory of biomedical research, Academician N.F. Izmerov Scientific-research Institute of Occupational Medicine. Address: 105275, Moscow, 31 Budennogo Avenue. Tel.: +7 (495) 365-59-41. E-mail: bezrukavnikovalm@mail.ru. ORCID: 0000-0002-0430-4154
Maria M. Kolyaskina, PhD, senior researcher of the Laboratory of biomedical research, Academician N.F. Izmerov Scientific-research Institute of Occupational Medicine, lecturer at the Department of occupational medicine, aviation, space and diving medicine, I.M. Sechenov First Moscow State Medical University of the Ministry of Healthcare of Russia (Sechenov University). Address: 105275, Moscow, 31 Budennogo Avenue. Tel.: +7 (495) 365-59-41. E-mail: koliaskina.mm@irioh.ru. ORCID: 0000-0001-5356-1598


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