A clinical case of early diagnosis of giant cell arteritis (Horton’s disease) in the practice of a general practitioner


DOI: https://dx.doi.org/10.18565/therapy.2023.10.132-138

Alieva A.M., Baykova I.E., Teplova N.V., Reznik E.V., Kotikova I.A., Nikitina O.S., Shabatina T.M., Nikitin I.G.

1) N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia, Moscow; 2) Scientific Clinical Center No. 2 of Academician B.V. Petrovsky Russian Scientific Center for Surgery, Moscow
Abstract. Giant cell arteritis (GCA) is a systemic vasculitis, the morphological feature of which is the frequent presence of giant multinucleated cells in the wall of the affected vessels. Although awareness of GCA has increased in recent years, its varied course still leads to diagnostic uncertainty. A high index of suspicion is a critical factor for early diagnosis. Clear diagnostic criteria, accessible specialist consultations and informative management recommendations are essential for rapid diagnosis and appropriate initiation of treatment. Timely administration of drug therapy helps prevent complications. Our article describes a clinical case of GCA in a 68-year-old patient. The interest of the clinical case is due, first of all, to early diagnosis, which made it possible to prescribe pathogenetic therapy in a short time, and, ultimately, to avoid the formidable complications characteristic of giant cell arteritis.

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About the Autors


Amina M. Alieva, PhD in Medical Sciences, associate professor of the Department of hospital therapy named after Academician G.I. Storozhakov of the Faculty of general medicine, N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia. Address: 117997, Moscow, 1 Ostrovityanova St.
E-mail: amisha_alieva@mail.ru
ORCID: https://orcid.org/0000-0001-5416-8579
Irina E. Baykova, PhD in Medical Sciences, associate professor of the Department of hospital therapy named after Academician G.I. Storozhakov of the Faculty of general medicine, N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia. Address: 117997, Moscow, 1 Ostrovityanova St.
ORCID: https://orcid.org/0000-0003-0886-6290
Natalya V. Teplova, MD, professor, head of the Department of clinical pharmacology of the Faculty of general medicine, N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia. Address: 117997, Moscow, 1 Ostrovityanova St.
ORCID: https://orcid.org/0000-0002-7181-4680
Elena V. Reznik, MD, associate professor, head of the Department of propaedeutics of internal diseases of the Faculty of general medicine, N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia. Address: 117997, Moscow, 1 Ostrovityanova St.
ORCID: https://orcid.org/0000-0001-7479-418X
Irina A. Kotikova, student of the Faculty of general medicine, N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia. Address: 117997, Moscow, 1 Ostrovityanova St.
E-mail: kotikova.ia@mail.ru
ORCID: https://orcid.org/0000-0001-5352-8499. SPIN code: 1423-7300
Olga S. Nikitina, cardiologist, therapist at Scientific Clinical Center No. 2 of Academician B.V. Petrovsky Russian Scientific Center for Surgery. Address: 117593, Moscow, 1А Litovskiy Boulevard.
ORCID: https://orcid.org/0009-0005-8436-1157
Tatyana M. Shabatina, clinical resident of the Department of hospital therapy named after academician G.I. Storozhakov of the Faculty of general medicine, N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia. Address: 117997, Moscow, 1 Ostrovityanova St.
ORCID: https://orcid.org/0009-0008-6024-680X
Igor G. Nikitin, MD, professor, head of the Department of hospital therapy named after academician G.I. Storozhakov of the Faculty of general medicine, N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia. Address: 117997, Moscow, 1 Ostrovityanova St.
ORCID: https://orcid.org/0000-0003-1699-0881


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