Comorbidity of chronic obstructive pulmonary disease and anemia: Clinical course peculiarities, diagnosis, therapy


DOI: https://dx.doi.org/10.18565/therapy.2024.1.104-111

Budnevsky A.V., Gubanov D.S., Bavykina I.A., Makeeva A.V., Budnevskaya S.A., Chernik T.A.

1) N.N. Burdenko Voronezh State Medical University of the Ministry of Healthcare of Russia; 2) G.R. Derzhavin Tambov State University
Abstract. Article is devoted to modern aspects of the clinical course of chronic obstructive pulmonary disease (COPD) and anemia of chronic diseases (ACD). Peculiarities of diseases accompanying COPD, data from studies analyzing frequency and severity of comorbid pathology, and its influence at the course of COPD are examined in details. Characteristic changes in laboratory indexes are introduced in case when a patient has COPD and ACD at the same time. The review also provides information on existing algorithms for differential diagnosis of anemia in patients with COPD, with an emphasis on the specifics of ferritin and erythropoietin metabolism in this group of patients. Special attention is paid to the results of studies indicating increased symptoms and worsening survival prognoses when COPD and anemia are combined all together. Data collected in the article emphasize the importance of timely detection and treatment of ACD in COPD patients.
Keywords: haemoglobin, anemia of chronic diseases, comorbidity, chronic obstructive pulmonary disease, ferritin
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About the Autors

Andrey V. Budnevsky, MD, Dr. Sci. (Medicine), professor, vice-rector for scientific and innovation activities, head of the Department of faculty therapy, N.N. Burdenko Voronezh State Medical University of the Ministry of Healthcare of Russia, Honored Inventor of the Russian Federation. Address: 393036, Voronezh, 10 Studencheskaya St.
E-mail: budnev@list.ru
ORCID: https://orcid.org/0000-0002-1171-2746
Dmitry S. Gubanov, MD, graduate student of the Department of faculty therapy, N.N. Burdenko Voronezh State Medical University of the Ministry of Healthcare of Russia, assistant at the Department of propaedeutics of internal diseases and faculty therapy, G.R. Derzhavin Tambov State University. Address: 392036, Tambov, 33 Internationalnaya St.
E-mail: dmitrij.gubanov@yandex.ru
ORCID: https://orcid.org/0009-0002-1853-0053
Irina A. Bavykina, MD, Dr. Sci. (Medicine), associate professor of the Department of faculty and palliative pediatrics, N.N. Burdenko Voronezh State Medical University of the Ministry of Healthcare of Russia. Address: 393036, Voronezh, 10 Studencheskaya St.
E-mail: i-bavikina@yandex.ru
ORCID: https://orcid.org/0000-0003-1062-7280
Anna V. Makeeva, PhD (Biology), associate professor of the Department of pathological physiology, N.N. Burdenko Voronezh State Medical University of the Ministry of Healthcare of Russia. Address: 393036, Voronezh, 10 Studen­cheskaya St.
E-mail: a.makeeva@vrngmu.ru
ORCID: https://orcid.org/0000-0002-4926-167Х
Sofia A. Budnevskaya, 3rd year student of the Faculty of general medicine, N.N. Burdenko Voronezh State Medical University of the Ministry of Healthcare of Russia. Address: 393036, Voronezh, 10 Studencheskaya St.
E-mail: Yuliyag36@gmail.com
ORCID: https://orcid.org/0000-0003-3649-5642
Tatyana A. Chernik, MD, PhD (Medicine), assistant at the Department of faculty therapy, N.N. Burdenko Voronezh State Medical University of the Ministry of Healthcare of Russia. Address: 393036, Voronezh, 10 Studencheskaya St.
E-mail: ch01@mail.ru
ORCID: https://orcid.org/0000-0003-1371-0848


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