Unsolved mysteries of “broken heart” syndrome


DOI: https://dx.doi.org/10.18565/therapy.2024.4.98-106

Kozlova A.A., Kokorin V.A.

1) N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia, Moscow; 2) RUDN University, Moscow
Abstract. Takotsubo syndrome (TS) is characterized by transient local systolic dysfunction, predominantly involving the apex and/or middle segment of the left heart ventricle, in the absence of thrombotic occlusion of the coronary arteries according to coronary angiography data. Clinically, TS resembles acute coronary syndrome and has similar electrocardiographic signs. Current review outlines modern ideas about the epidemiology, predisposing factors, triggers, diagnostic criteria and prognosis for TS, and also highlights the main approaches to the treatment of this disease. Taking into account the range of remaining questions, further research is needed to examine prognosis and develop clinical recommendations for the treatment and prevention of TS.
Keywords: prognosis for takotsubo syndrome, treatment of takotsubo syndrome, diagnosis of takotsubo syndrome, stress-induced cardiomyopathy, Takotsubo syndrome
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About the Autors

Anna A. Kozlova, MD, assistant at the Department of hospital therapy named after academician P.E. Lukomsky of the Faculty of general medicine, N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia. Address: 117997, Moscow, 1 Ostrovityanova St.
E-mail: nnakoz15@mail.ru
ORCID: https://orcid.org/0009-0002-4321-1927
Valentin A. Kokorin, MD, Dr. Sci. (Medicine), associate professor, professor of the Department of hospital therapy named after academician P.E. Lukomsky of the Faculty of general medicine N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia, professor of the Department of hospital therapy with courses in endocrinology, hematology and clinical laboratory diagnostics, RUDN University. Address: 117997, Moscow, 1 Ostrovityanova St.
E-mail: valentinkokorin@yahoo.com
ORCID: https://orcid.org/0000-0001-8614-6542


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