№4 / 2022

ORIGINAL STUDIES
Barteneva A.S., Vorobyeva N.A.
Pharmacogenetic testing as an element of personalized medicine in real clinical practice 		7-14
Vorobyeva N.A., Vorobyeva A.I., Shchapkov A.A.
Hemorrhagic complications of antithrombotic therapy in real clinical practice 		15-22
Zhuchkova S.M., Busalaeva E.I., Karamalikov S.A.
The role of the general practitioner in detecting side effects in the application of anticancer drugs 		23-30
Izmozherova N.V., Popov A.A., Ryabinina A.V., Vikhareva А.A., Safianik E.A., Spevak A.V.
Analysis of the BsmI (rs1544410) polymorphism of the vitamin D receptor gene and the clinical effect of 25(OH)D level correction in a population of late postmenopausal women in Yekaterinburg 		31-40
Krasnova N.M., Nikolaev V.M., Efremova E.N., Egorova A.A., Tatarinova T.E., Maksimova N.E., Prokopev E.S., Kravchenko A.F., Tatarinova O.V., Vengerovsky A.I., Sychev D.A.
Dependence of pharmacokinetics and hepatotoxic action of isoniazid on its acetylation rate in patients with drug-sensitive pulmonary tuberculosis 		41-48
Nikitin E.Yu., Drozdov V.N., Vorobyeva O.A., Astapovsky A.A., Khalaidzheva K.N., Shikh E.V.
Prognostic and diagnostic value of NGAL and KIM-1 in patients with acute kidney injury treated with antibiotics 		49-55
Osipyan Е.Ae., Makhova A.A., Drozdov V.N., Shikh E.V.
The effect of increased hepcidin expression on the pharmacokinetics of ferrous sulfate in patients with iron deficiency on the background of anemia of chronic diseases 		56-61
Tufanova O.S., Kasimova A.R., Gordina E.M., Rukina A.N., Bozhkova S.A.
Pharmacoeconomic study of the use of fosfomycin and fluoroquinolones for urinary tract sanitation in orthopaedic patients 		62-70
Eremina E.Yu., Gerasimenko I.V., Lityushkina M.I., Strokova O.A.
Features of the course of pseudomembranous colitis in patients infected with SARS-CoV-2 		71-76
Didigova R.T., Malsagova I.Ya., Buzurtanova M.B., Ugurchieva P.O., Edilgirieva L.A.
Assessment of the condition of the coronary arteries in persons with angina pectoris in combination with or without type 2 diabetes 		77-80
REVIEWS
Astapovsky A.A., Drozdov V.N., Shikh E.V., Lazareva N.B.
Adrenomedullin: biological functions and prospects for use as a biomarker in clinical practice 		81-90
Gomon Yu.M., Kolbin A.S., Strizheletsky V.V., Ivanov I.G., Sultanova F.M., Balykina Yu.E., Verbitskaya E.V.
A systematic review with meta-analysis of the safety of Janus kinase inhibitors in relation to the risks of secondary bacterial infections 		91-100
Aliev A.M., Reznik E.V., Teplova N.V., Arakelyan R.A., Shnahova L.M., Baykova I.E., Akkieva M.A., Nikitin I.G.
Interleukin 37 is a new biological marker for cardiovacular pathology 		101-109
GUIDELINES FOR PRACTITIONERS
Bulanova N.A., Panchenkova L.A., Khamidova Kh.A., Karnuta G.G., Zinovieva S.Yu., Yurkova T.E., Khomyakova T.D., Khromova E.S., Popov V.V.
Anemia of chronic disease in a female patient, heterozygous for H63D HFE gene mutation 		110-114
Gasanov M.Z., Kharkov A.S., Shevchenko S.V., Salaychuk E.V., Terentyev A.A., Savchenko A.A.
Late diagnosis of anterior mediastinum mature teratoma 		115-118
Tarasova L.V., Dubova A.V., Dimitrieva O.V., Khripunova O.N.
Thorny path to the diagnosis of «amyloidosis of the heart» 		119-125
Postnikova L.B., Gudim A.L., Pasechnik N.N., Kozyrev S.V., Troyan V.N.
Difficulties of early diagnosis of heart sarcoma: case from practice 		126-132
Guideline for practitioners
Review of the book «Endocardium and cardiac valves in systemic rheumatic diseases» (Yagoda A.V., Gladkikh N.N.; Stavropol: IRC «Fabula», 2021) 		133
ACTUAL ISSUES OF PHARMACOTHERAPY
Vorobyeva N.M., Tkacheva O.N.
Safety of antithrombotic therapy in cardiological practice: how to protect tunica mucosa of gastrointestinal tract? 		134-140
Polyakova O.A., Ostroumova O.D. , Arablinsky A.V.
Drug safety and polymorbidity as important components of rational pharmacotherapy in cardiology 		141-148
Activities of RNMOT
Interregional research and practical conferences, round tables and educational seminars of RSMSIM (April – May 2022) 		149-152
WE REMEMBER
Our contemporary person: to the 80th anniversary of the birth of Yu.B. BELOUSOV 		153-156

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