Modelling of parameters lipid a spectrum depending on age and size of an index of weight of a body at patients with clinical forms of ischemic illness of heart


B.B. Fishman, A.I. Khorochevskaya, V.V. Zurabov, А.V. Savolyuk, N.О. Zhbanova, S.SH. Butrimova, I.V. Prozorova, D.A. Shamiladze, O.U.Lole

Yaroslav-The-Wise Novgorod State University Ministry of Education and Science of the Russian Federation, Veliky Novgorod
Aim. Modelling, lipid a spectrum, ischemic illness of heart. Materials and methods. The study included 210 patients with CAD with stable angina; 215 patients with CAD, who previously had myocardial infarction (MI), and 215 patients with CAD and heart failure (HF). Results. As have shown our calculations, the age of patients has the expressed value. So, at various structure of age groups parameters total cholesterol, LDL and HDL have mathematical distinctions at various groups of diseases. To evaluate lipid spectrum dependence on age and the BMI, analysis was conducted, visualized by ternary diagrams, with approximate equations. These approximate equations had grouping variables of the age of patients for each disease group and variables as total cholesterol, LDL and HDL, taking into account gender and the variables in the form. According to our calculations, the age of patients is clearly expressed. Thus, in different structure of various age groups, BMI such indicators total cholesterol, LDL and HDL, have mathematical differences in different groups of diseases. Conclusion. It is proved that dyslipidemia is essentially a biochemical manifestation of lipid metabolism disorders, which may result in significant morphological and functional disorders in the body. Our analysis revealed significant changes in the lipid spectrum, indicating a high risk of further development of atherosclerosis and its complications in the patients observed. Thus, mathematical models allow to calculate the values of total cholesterol, HDL and LDL, depending of age groups and BMI value in patients with myocardial infarction, angina, heart failure, taking gender into account.
Keywords: ischemic illness of heart, lipid spectrum, dynamics model
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About the Autors

Boris В. Fishman, MD, рrofessor of Additional Professional Education Department, Institute For Medical Education, Yaroslav-the-Wise Novgorod State University. Adress: 173016, Veliky Novgorod, Chimikov st., 11.
Tel.: 79318531339. E-mail: fishman@mxc.ru

Alla I. Horoshevskaja, head physician of the Novgorod regional clinical hospital, candidate of medical sciences, competitor of a doctor’s degree NovGu

Svetlana Sh. Butrimova, the senior teacher of faculty of internal illnesses NovGu, assistant to the head physician by a medical part, Great Novgorod, competitor NovGu

Irina V. Prozorova, candidate of medical sciences, the senior teacher of faculty of internal illnesses, competitor of a doctor’s degree

Antonina V. Savolyuk, postgraduate student (correspondence courses) Novgorod State University, Head of Hospital №3, Central Clinical Hospital, Veliky Novgorod

Natalia О. Zhbanova, postgraduate student (correspondence courses), Novgorod State University, doctor, Hospital №4, Central Clinical Hospital, Veliky Novgorod

Vacheslav V. Zurabov, postgraduate student (correspondence courses), Novgorod State University

David A. Shamiladze, postgraduate student (correspondence courses), Novgorod State University

Oksana Yu. Lole, Managing therapeutic branch of the Central city clinical hospital, Veliky Novgorod, competitor NovGu


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