Comorbidity of epilepsy and heart rhythm and conduction disturbance


DOI: https://dx.doi.org/10.18565/therapy.2021.5.60-65

Burd S.G., Mironov M.B., Rubleva Yu.V., Tairova R.T.

1) N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia, Moscow; 2) Federal Center of Brain Research and Neurotechnologies of FMBA of Russia, Moscow
Abstract. Article considers various options for the comorbidity of epilepsy and cardiac arrhythmias and conduction disorders. Epilepsy can be a complication of cardiovascular disease and stroke, but at the same time, epilepsy by itself or antiepileptic drugs therapy can lead to heart rhythm and conduction disturbances. Literature data on the incidence of early and late symptomatic attacks, as well as post-stroke epilepsy in patients after acute cerebrovascular accident are introduced. The problem of drug interactions between anticoagulant, antiarrhythmic and antiepileptic drugs in patients with a history of cardioembolic stroke and comorbid epilepsy is discussed. The point of differential diagnosis of epileptic paroxysms and syncope conditions of cardiac genesis is considered.
Keywords: heart rhythm and conduction disturbances, epileptic seizures, epilepsy
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About the Autors

Sergey G. Burd, MD, professor of the Department of neurology, neurosurgery and medical genetics of the Faculty of general medicine, N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia, head of the Department of epilepsy and paroxysmal diseases, Federal Center of Brain Research and Neurotechnologies of FMBA of Russia. Address: 177997, Moscow, 1/10 Ostrovityanova Str. Tel.: +7 (901) 548-17-85. E-mail: burds@yandex.ru. ORCID: 0000-0003-0804-7076
Mikhail B. Mironov, PhD, leading researcher of the Department of epilepsy and paroxysmal diseases, Federal Center of Brain Research and Neurotechnologies of FMBA of Russia. Address: 177997, Moscow, 1/10 Ostrovityanova Str. ORCID: 0000-0003-4844-8042
Yulia V. Rubleva, PhD, senior researcher of the Department of epilepsy and paroxysmal diseases, head of the Department of neurology, Federal Center of Brain Research and Neurotechnologies of FMBA of Russia. Address: 177997, Moscow, 1/10 Ostrovityanova Str. ORCID: 0000-0002-3746-1797
Nina V. Kukina, junior researcher of the Department of epilepsy and paroxysmal diseases, FSBI Federal Center of Brain Research and Neurotechnologies of FMBA of Russia. Address: 177997, Moscow, 1/10 Ostrovityanova Str.
Raisa T. Tairova, PhD, Deputy Director for clinical care, chief physician of Federal Center of Brain Research and Neurotechnologies of FMBA of Russia. Address: 177997, Moscow, 1/10 Ostrovityanova Str. Tel.: +7 (926) 226-59-88. E-mail: tairova-r@mail.ru. ORCID: 0000-0002-4174-7114


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