Therapy » Non-alcoholic fatty liver disease and atherosclerosis: common mechanisms of development and progression

Non-alcoholic fatty liver disease and atherosclerosis: common mechanisms of development and progression

DOI: https://dx.doi.org/10.18565/therapy.2021.7.118-125

Kuznetsova A.S., Genkel V.V., Dolgushina A.I., Shaposhnik I.I, Olevskaya E.R., Selyanina A.A., Khusainova G.M.
South Ural State Medical University of the Ministry of Healthcare of the Russia, Chelyabinsk

Abstract. Non-alcoholic fatty liver disease (NAFLD) is an urgent medical and social problem, representing the most widespread liver disease. Different mechanisms of joint progression of liver fibrosis and atherosclerosis, which determine the development of cardiovascular accidents and adverse liver-related outcomes, have now been identified. Patients with NAFLD with initially significant liver fibrosis or its progression according to the data of dynamic monitoring should be considered as patients with increased cardiovascular risk. The development and optimization of dynamic monitoring protocols by an interdisciplinary team of specialists is of critical importance for this category of patients.

Keywords: Kew words: non-alcoholic fatty liver disease, atherosclerosis, dyslipidemia, diabetes mellitus, cardiovascular events, Russian and foreign bases for citing scientific sources

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About the Autors

Alla S. Kuznetsova, PhD, associate professor of the Department of hospital therapy, South Ural State Medical University of the Ministry of Healthcare of the Russia. Address: 454092, г. Chelyabinsk, 64 Vorovskogo Str. Tel.: +7 (968) 113-91-69. E-mail: kuzja321@mail.ru. ORCID: 0000-0002-1136-7284
Vadim V. Genkel, associate professor of the Department of propedeutics of internal diseases, South Ural State Medical University of the Ministry of Healthcare of the Russia. Address: 454092, г. Chelyabinsk, 64 Vorovskogo Str. Tel.: +7 (951) 441-70-61. E-mail: henkel-07@mail.ru. ORCID: 0000-0001-5902-3803
Anastasia I. Dolgushina, MD, head of the Department of hospital therapy, South Ural State Medical University of the Ministry of Healthcare of the Russia. Address: 454092, г. Chelyabinsk, 64 Vorovskogo Str. Tel.: +7 (963) 463-30-69. E-mail: dolgushinaai@yandex.ru. ORCID: 0000-0003-2569-1699
Igor I. Shaposhnik, MD, head of the Department of propedeutics of internal diseases, South Ural State Medical University of the Ministry of Healthcare of the Russia. Address: 454092, г. Chelyabinsk, 64 Vorovskogo Str. Tel.: +7 (908) 823-51-20. E-mail: shaposhnik@yandex.ru. ORCID: 0000-0002-7731-7730
Elena R. Olevskaya, MD, associate professor of the Department of hospital surgery, South Ural State Medical University of the Ministry of Healthcare of the Russia. Address: 454092, г. Chelyabinsk, 64 Vorovskogo Str. Tel.: +7 (922) 230-02-22. E-mail: endo74@mail.ru. ORCID: 0000-0002-7385-8505
Anna A. Selyanina, assistant at the Department of hospital therapy, South Ural State Medical University of the Ministry of Healthcare of the Russia. Address: 454092, г. Chelyabinsk, 64 Vorovskogo Str. E-mail: anna-selyanina@mail.ru. ORCID: 0000-0002-3481-8092
Guzel M.Khusainova, assistant at the Department of hospital therapy, South Ural State Medical University of the Ministry of Healthcare of the Russia. Address: 454092, г. Chelyabinsk, 64 Vorovskogo Str. Tel.: +7 (963) 472-98-03 E-mail: husainovagm@yandex.ru. ORCID: 0000-0001-5954-3112

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