Still’s disease is a great mimic of systemic inflammatory response syndrome?


DOI: https://dx.doi.org/10.18565/therapy.2023.2.80-84

Melnikova L.V., Lokhina T.V., Berenshtein N.V., Timofeeva N.A.

1) Russian Medical Academy of Continuous Professional Education of the Ministry of Healthcare of Russia, Moscow; 2) Penza Institute for Further Training of Physicians – branch of Russian Medical Academy of Continuous Professional Education of the Ministry of Healthcare of Russia; 3) G.A. Zakharyin Clinical Hospital No. 6, Penza
Abstract. Still’s disease in adults (ADS) is a rare systemic autoinflammatory disease. Fever, arthralgia, rash, and neutrophilic leukocytosis are dominating in its clinical picture. These indexes let doctors to suspect infectious diseases, sepsis and prescribe antibiotic therapy, which is ineffective. Article presents a case of a disease that debuted with high fever, shortness of breath, severe weakness and myalgia. Female patient was diagnosed according to the present symptoms, laboratory signs, taking into account the criteria of Yamaguchi M. et al. and by excluding infectious and autoimmune diseases, malignant neoplasms. Treatment with corticosteroids resulted in complete clinical remission.
Keywords: systemic autoinflammatory disease, Still’s disease in adults, sepsis
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About the Autors

Lyudmila V. Melnikova, MD, associate professor, professor the Department of general medical practice and polyclinic therapy, Russian Medical Academy of Continuous Professional Education of the Ministry of Healthcare of Russia, Moscow. Address: 125445, Moscow, 19/38 Belomorskaya Str. E-mail: lumel2408@yandex.ru. ORCID: https://orcid.org/0000-0003-4688-1272
Tatyana V. Lokhina, MD, head of the Department of therapy, cardiology, functional diagnostics and rheumatology, Penza Institute for Further Training of Physicians – branch of Russian Medical Academy of Continuous Professional Education of the Ministry of Healthcare of Russia. Address: 440060, Penza, 8A Stasova Str. E-mail: ltv-13@mail.ru. ORCID: https://orcid.org/0000-0002-9493-444X
Natalya V. Berenshtein, PhD in Medical Sciences, associate professor of the Department of ultrasound diagnostics, Penza Institute for Further Training of Physicians – branch of Russian Medical Academy of Continuous Professional Education of the Ministry of Healthcare of Russia. Address: 440060, Penza, 8A Stasova Str. E-mail: berenshtein2011@yandex.ru. ORCID: https://orcid.org/0000-0002-1589-2799
Natalya A. Timofeeva, deputy chief physician for medicine of G.A. Zakharyin Clinical Hospital No. 6. Address: 440071, Penza, 7 Stasova Str. E-mail: nataliatimofeeva1805@gmail.com


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