Impact of novel coronavirus infection COVID-19 on the development of acute kidney injury and peculiarities of chronic kidney disease clinical course: Literature review


DOI: https://dx.doi.org/10.18565/therapy.2023.3.61-68

Bochkareva V.O., Demko I.V., Petrova M.M., Obukhova I.A., Kozlov E.V.

1) N.S. Karpovich Krasnoyarsk Interdistrict Clinical Emergency Hospital; 2) Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University of the Ministry of Healthcare of Russia
Abstract. Article discusses the impact of a new coronavirus infection at the kidneys, namely the predictors and mechanism of acute kidney injury (AKI) development, the impact of COVID-19 at chronic renal failure progression. A comparison was made of the severity of the disease, mortality rate, need for ICU treatment and necessity for mechanical ventilation in CKD patients. The results of original studies devoted to these problems are analyzed. The data presented in the article confirm that AKI is one of the most frequent complications of severe course of coronavirus infection, while mechanical ventilation is the main predictor of AKI. Patients with chronic kidney disease have been found to have higher mortality, hospitalization rates, and need for mechanical ventilation in case of COVID-19 than patients without that kind of pathology.
Keywords: SARS-CoV-2, COVID-19, kidneys, chronic kidney disease, acute kidney injury
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About the Autors

Veronika O. Bochkareva, pulmonologist at N.S. Karpovich Krasnoyarsk Interdistrict Clinical Emergency Hospital. Address: 660041, Krasnoyarsk, 17/3 Kurchatova Str. E-mail: bramma-ska@mail.ru
Irina V. Demko, MD, professor, head of the Department of hospital therapy and immunology with a course of professional development, Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University of the Ministry of Healthcare of Russia. Address: 660022, Krasnoyarsk, 1 Partizana Zheleznyaka Str. E-mail: demko64@mail.ru
Marina M. Petrova, MD, professor, head of the Department of polyclinic therapy and family medicine with a course of professional development, Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University of the Ministry of Healthcare of Russia. Address: 660022, Krasnoyarsk, 1 Partizana Zheleznyaka Str. E-mail: stk99@yandex.ru
Irina A. Obukhova, pulmonologist at N.S. Karpovich Krasnoyarsk Interdistrict Clinical Emergency Hospital. Address: 660041, Krasnoyarsk, 17/3 Kurchatova Str. E-mail: tolpyga256@gmail.com
Evgeny V. Kozlov, head of the Department of pulmonology, N.S. Karpovich Krasnoyarsk Interdistrict Clinical Emergency Hospital. Address: 660041, Krasnoyarsk, 17/3 Kurchatova Str. E-mail: kev-pulmonolog@mail.ru


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