Evaluating processes of cardiac remodeling in the development of chronic thromboembolic pulmonary hypertension


V.S. Shemenkova, N.A. Shostak, A.A. Klimenko, A.A. Bogdanova, D.P. Kotova

1 Russian National Research Medical University named after N.I. Pirogov, Moscow 2 Clinical Hospital № 1 named after N.I. Pirogov, Moscow
The aim. To evaluate the processes of remodeling of the right and left heart in patients with chronic thromboembolic pulmonary hypertension (CTEPH). Material and methods. The study included 30 patients who underwent in-patient examination and treatment at the State Clinical Hospital №1 named after N.I. Pirogov, Moscow, to confirm the diagnosis of CTEPH and the selection of drug therapy. For all patients, one expert performed an echocardiographic (EchoCG) study to evaluate the parameters of the right and left parts of the heart. Results. Statistically significant correlations between the severity of СTEPH flow and the structural and functional parameters of the right and left parts of the heart were obtained. Conclusions. The evaluation of structural and functional echocardiographic parameters of cardiac remodeling in patients with CTEPH was performed. Correlation links between severity of the disease course and echocardiographic data are revealed, which allows a simple, non-invasive method to conduct dynamic observation of patients and to identify prognostically unfavorable factors of СTEPH course.

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About the Autors


Victoria S. Shemenkova, PhD candidate of the acad. A.I. Nesterov Chair of Intermediate Level Therapy of N.I.Pirogov RNRMU; therapist of N.I. Pirogov City Clinical Hospital № 1. N.I. Pirogov RNRMU Federal State Budgetary Educational Institution of Higher Education of the Ministry of Healthcare of Russia. Address: Russia, 117997, 1 Ostrovityanova Str. E-mail: vshemenkova@mail.ru

Nadezhda A. Shostak, MD., professor, head of the acad. A.I. Nesterov Chair of Intermediate Level Therapy of N.I. Pirogov RNRMU. Address: Russia, 117997, 1 Ostrovityanova Str. E-mail: shostakkaf@yandex.ru

Alesya A. Klimenko, PhD., associate professor of the acad. A.I. Nesterov Chair of Intermediate Level Therapy of
N.I. Pirogov RNRMU. Address: Russia, 117997, 1 Ostrovityanova Str. E-mail: shostakkaf@yandex.ru

Aleksandra A. Bogdanova, PhD, head of the Department of functional diagnostics of N.I. Pirogov City Clinical Hospital № 1 of the department of health of Moscow. Address: Russia, 117049, Moscow, 8 Leninsky prospect Str. E-mail: doc.aabogdanova@mail.ru

Darja P. Kotova, PhD., head of the Department of therapy of N.I. Pirogov City Clinical Hospital № 1, associate professor of acad. A.I. Nesterov Chair of Intermediate Level Therapy of N.I. Pirogov RNRMU of the Ministry of Healthcare of Russia. Address: Russia, 117997, 1 Ostrovityanova Str. E-mail: doc.kotova@mail.ru


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