Correction of symptoms of meteosensitivity in arterial hypertension patients
DOI: https://dx.doi.org/10.18565/therapy.2018.6.111-120
O.A. Kislyak, T.B. Kasatova, S.L. Postnikov
Chair of faculty therapy of general medicine Department of FSBEI of HE «N.I. Pirogov Russian national research medical university»
Existing data from the scientific literature are indicating at correlation between the presence of pathological meteosensitivity, its severity and the degree of arterial hypertension.
The purpose of the study is to estimate changes in the frequency and severity of symptoms associated with adverse meteorological conditions in patients 40–70 years of age with cerebrovascular disease in combination with stable hypertension on the phone of treatment with Ginkoum® medicine.
Material and methods. During the period of the study, starting from screening visit and following 4 visits with 30-day intervals, the schedule of previously prescribed planned antihypertensive therapy did not change. Ginkoum® was prescribed in a daily dose of 240 mg for the period of 102 to 114 days, depending on the timing of the patient’s scheduled visits. All patients throughout the study wrote diaries about their antihypertensive drugs intake and meteosensitivity. Evaluation of keeping diaries took place during all 4 scheduled visits.
Results. On the phone of Ginkoum® therapy to the moment of study completion, according to subjective estimation of patients, there was a decrease of average number of days with increased meteosensitivity symptoms, by 25% comparatively with the initial 30-day observation period on the phone of basic therapy. The dynamics of the proportion of days with unfavorable weather and symptoms of increased meteosensitivity from all days with unfavorable weather during Ginkoum® therapy after 60 days decreased from 28% to 18% and then remained at the same level of 19%.
Conclusion. Ginkoum® reduces the number of days with meteosensitivity-reflecting symptoms and reduces the severity of meteopathic reactions in patients with cerebrovascular disease and hypertension.
Keywords: meteosensitivity, arterial hypertension, cerebrovascular disease, standardized extract of ginkgo biloba
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About the Autors
Oksana A. Kislyak, MD, professor, head of the Chair of faculty therapy of general medicine Department of FSBEI of HE «N.I. Pirogov Russian national research medical university» of the Ministry of Health of Russia. 117997, Moscow, 1 Ostrovityanova St.Tel.: +79036162020, e-mail: kisliakoa@mail.ru
Tatyana B. Kasatova, PhD, associate professor of the Chair of faculty therapy of general medicine Department of FSBEI of HE «N.I. Pirogov Russian national research medical university» of the Ministry of Health of Russia. 117997, Moscow, 1 Ostrovityanova St.
Svetlana L. Postnikova, PhD, associate professor of the Chair of faculty therapy of general medicine Department of FSBEI of HE «N.I. Pirogov Russian national research medical university» of the Ministry of Health of Russia. 117997, Moscow, 1 Ostrovityanova St.