Clinical observation of a young patient with obesity and COVID-19-associated lung tissue damage


DOI: https://dx.doi.org/10.18565/therapy.2020.8.156-161

Larina V.N., Bondarenkova A.A.

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia, Moscow
COVID-19 infection is an up-to-date problem in modern medicine due to its high contagiousness and frequent development in young people. A clinical observation of 38-year-old patient complaining of dry cough, high fever, shortness of breath, weakness, with confirmed diagnosis of moderate bilateral polysegmental pneumonia and confirmed contact with COVID-19 patient is presented. Management of the patient is discussed.
Keywords: SARS-CoV-2, COVID-19, community-acquired pneumonia, management, obesity
Read entire article

Literature


  1. Chen T., Wu D., Cheng H. et al. Clinical characteristics of 113 deceased patients with coronavirus disease 2019: Retrospective study. BMJ. 2020; 368: m1091. doi: 10.1136/bmj.m1091.

  2. Chen N., Zhou M., Dong X. et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: A descriptive study. Lancet. 2020; 395(10223): 507–13. doi: 10.1016/S0140-6736(20)30211-7.

  3. Szymanek-Pasternak A., Serafinska S., Kucharska M., Szymanski Krzysztof Simon W. Severe course of COVID-19 in a middle-aged man without risk factors. Published online: April 03, 2020. doi: 10.20452/pamw.15277.

  4. Sabri A., Taheri M.S., Mahdavi A., Dobranowski J. 63-year-old male treated for COVID-19. Published online: March 31, 2020. doi: 10.20452/pamw.15271.

  5. Lagunas Rangel F.A. Neutrophil to lymphocyte ratio and lymphocyte to C reactive protein ratio in patients with severe coronavirus disease 2019 (COVID-19): A meta analysis. J Med Virol. 2020 Apr 3; 10.1002/jmv.25819. doi: 10.1002/jmv.25819. Online ahead of print.

  6. Белоцерковская Ю.Г., Романовских А.Г., Смирнов И.П. COVID-19: респираторная инфекция, вызванная новым коронавирусом: новые данные об эпидемиологии, клиническом течении, ведении пациентов. Consilium Medicum. 2020; 3: 12–20. [Belotserkovskaia Yu.G., Romanovskikh A.G., Smirnov I.P. COVID-19: a respiratory infection caused by new coronavirus: new data on epidemiology, clinical course, and patients management. Consilium Medicum. 2020; 3: 12–20 (In Russ.)]. doi: 10.26442/20751753.2020.3.200092.

  7. Qingmei H., Qingqing L., Shenhe J., Liangshun Y. Recent insights into 2019-nCoV: a brief but comprehensive review. J Infect. 2020; 80(4): 373–77. doi: 10.1016/j.jinf.2020.02.010.

  8. Garg S., Kim L., Whitaker M. et al. Hospitalization rates and characteristics of patients hospitalized with laboratory-confirmed coronavirus disease 2019 − COVID-NET, 14 states, march 1–30, 2020. MMWR Morb Mortal WklyRep. 2020; 69(15): 458–64. doi: 10.15585/mmwr.mm6915e3.

  9. Simmonet A., Chetboun M., Poissy J. et al. High prevalence of obesity in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) requiring invasive mechanical ventilation. Obesity (Silver Spring). 2020; 28(7): 1195–99. doi: 10.1002/oby.22831.

  10. Wang D., Hu B., Hu C. et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus – infected pneumonia in Wuhan, China. JAMA. 2020; 323(11): 1061–69. doi: 10.1001/jama.2020.1585.

  11. Временные методические рекомендации Министерства здравоохранения Российской Федерации: профилактика, диагностика и лечение новой коронавирусной инфекции (COVID-19). Версия 4 от 27.03.2020. [Temporary guidelines of the Ministry of Healthcare of Russia for the prevention, diagnosis and treatment of new coronavirus infection (COVID-19). Version 4 dated 27.03.2020 (In Russ.)].

  12. Временные методические рекомендации Министерства здравоохранения Российской Федерации: профилактика, диагностика и лечение новой коронавирусной инфекции COVID-19. Версия 7 от 03.06.2020. [Temporary guidelines of the Ministry of Healthcare of Russia for the prevention, diagnosis and treatment of new coronavirus infection (COVID-19). Version 7 dated 03.06.2020 (In Russ.)].

  13. Clinical management of COVID-19 Interim Guidance – May 2020. Geneva: World Health Organization; 2020. URL: https://www.who.int/publications-detail/clinical-management-of-covid-19 (date of access – 01.11.2020).

  14. Vargas-Vargas M., Cortes-Rojo C. Ferritin levels and COVID-19.Rev Panam Salud Publica. 2020; 44: e72. doi: 10.26633/RPSP.2020.72.

  15. World Health Organization. 2020. Clinical management of COVID-19: interim guidance, 27 May 2020. URL: https://apps.who.int/iris/handle/10665/332196 (date of access – 01.11.2020).

  16. Huang I., Pranata R., Lim A.M. et al. C-reactive protein, procalcitonin, D-dimer, and ferritin in severe coronavirus disease-2019: a meta-analysis. Ther Adv Respir Dis. 2020; 14: 1753466620937175. doi: 10.1177/1753466620937175.

  17. Guo T., Fan Y., Chen M. et al. Association of cardiovascular disease and myocardial injury with outcomes of patients hospitalized with 2019-coronavirus disease (COVID-19). JAMA Cardiol. 2020; 5(7): 811–18. doi:10.1001/jamacardio.2020.1017.

  18. Чучалин А.Г. Биологические маркеры при респираторных заболеваниях. Терапевтический архив. 2014; 3: 4–13. [Chuchaun A.G. Biological markers in respiratory diseases. Terapevticheskiy arkhiv. 2014; 3: 4–13 (In Russ.)].


About the Autors

Vera N. Larina, MD, associate professor, head of the Department of polyclinic therapy of medical faculty of N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia. Address: 117997, Moscow,
1 Ostrovityaninov Str. Tel.: + (910) 473-35-66. E-mail: larinav@mail.ru. ORCID: 0000-0001-7825-5597
Alina A. Bondarenkova, resident of the Department of polyclinic therapy of medical faculty of N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia. Address: 117997, Moscow, 1 Ostrovityaninov Str. ORCID: 0000-0002-0673-5775


Similar Articles

Back to Content

Бионика Медиа