Osteoporosis and comorbidity


DOI: https://dx.doi.org/10.18565/therapy.2021.10.127-131

Zhugrova E.S., Mazurov V.I.

I.I. Mechnikov North-Western State Medical University of the Ministry of Healthcare of Russia, Saint Petersburg
Abstract. Osteoporosis leads to an increased risk of fractures. Menopause and aging are the most common causes of that pathology. Taking into account that aging populations are rapidly increasing in many countries, osteoporosis can become a global problem that affects life quality of many people. There is a well-known correlation between comorbidity and bone loss and fractures. This study briefly reflects comorbid pathology such as cardiovascular, cerebrovascular diseases, degenerative joint lesions, diabetes mellitus, bronchial asthma, COPD, etc., which affect the course of osteoporosis and the progression of fractures.

Literature



  1. Ховасова Н.О., Наумов А.В., Ткачева О.Н., Дудинская Е.Н. Характеристика гериатрического и соматического статуса у пациентов с остеопорозом. Проблемы эндокринологии. 2021; 3: 45–54. [Khovasova N.O., Naumov A.V., Tkacheva O.N., Dudinskaya E.N. Characteristics of geriatric and somatic status in patients with osteoporosis. Problemy endokrinologii = Issues of Endocrinology. 2021; 3: 45–54 (In Russ.)]. https://dx.doi.org/10.14341/probl12751.

  2. Беляева Е.А., Хадарцев А.А. Коморбидная патология при осложненном постменопаузальном остеопорозе. Вопросы организации и информатизации здравоохранения. 2016; S: 59–61. [Belyayeva Ye.A., Khadartsev A.A. Comorbid pathology in complicated postmenopausal osteoporosis. Voprosy organizatsii i informatizatsii zdravookhraneniya = Organization and Informatization of Healthcare. 2016; S: 59–61 (In Russ.)].

  3. Farhat G.N., Cauley J.A. The link between osteoporosis and cardiovascular disease. Clin Cases Miner Bone Metab. 2008; 5(1): 19–34.

  4. Szekanecz Z., Raterman H.G., Petho Z. et al. Common mechanisms and holistic care in atherosclerosis and osteoporosis. Arthritis Res Ther. 2019; 21(1): 15. doi: 10.1186/s13075-018-1805-7.

  5. Chen S.J., Lin C.S., Lin C.L., Kao C.H. Osteoporosis is associated with high risk for coronary heart disease: A population-based cohort study. Medicine (Baltimore). 2015; 94(27): e1146. doi: 10.1097/MD.0000000000001146.

  6. West S.L., O’Donnell E. Cardiovascular disease and bone loss-new research in identifying common disease pathophysiologies and predictors. AME Med J. 2018; 3(3): 42. doi: 10.21037/amj.2018.03.08.

  7. Ye Z., Lu H., Liu P. Association between essential hypertension and bone mineral density: a systematic review and meta-analysis. Oncotarget. 2017; 8(40): 68916–27. doi: 10.18632/oncotarget.20325.

  8. Nakagami H., Morishita R. [Hypertension and osteoporosis]. Clin Calcium. 2013; 23(4): 497–503 (In Japanese).

  9. Chen M., Li Y., Huang X. et al. Skeleton-vasculature chain reaction: a novel insight into the mystery of homeostasis. Bone Res. 2021; 9(1): 21. doi: 10.1038/s41413-021-00138-0.

  10. Etienne J. Bisson, Marcia L. et al. Multiple sclerosis is associated with low bone mineral density and osteoporosis. Neurol Clin Pract Oct. 2019; 9(5): 391–99. doi: 10.1212/CPJ.0669.

  11. Sany J., Bourgeois P., Saraux A. et al. Characteristics of patients with rheumatoid arthritis in France: a study of 1109 patients managed by hospital based rheumatologists. Ann Rheum Dis. 2004; 63(10): 1235–40. doi: 10.1136/ard.2003.013110.

  12. Orres R.A., Welte T., Bals R. et al. [Systemic manifestations and comorbidities in patients with chronic obstructive pulmonary disease (COPD) and their effect on clinical state and course of the disease an overview of the cohort study COSYCONET]. Dtsch Med Wochenschr. 2010; 135(10): 446–49 (In German). doi: 10.1055/s-0030-1249185.

  13. Kumarathas I., Harslof T., Andersen C.U. et al. The risk of osteoporosis in patients with asthma. Eur Clin Respir J. 2020; 7(1): 1763612. doi: 10.1080/20018525.2020.1763612.

  14. Sarkar M., Bhardwaj R., Madabhavi I., Khatana J. Osteoporosis in chronic obstructive pulmonary disease. Clin Med Insights Circ Respir Pulm Med. 2015; 9: 5–21. doi: 10.4137/CCRPM.S22803.


About the Autors


Elena S. Zhugrova, PhD, associate professor of the Department of therapy, rheumatology, examination of temporary disability and quality of medical care named after E.E. Eichwald, I.I. Mechnikov North-West State Medical University of the Ministry of Healthcare of Russia. Address: 191015, Saint Petersburg, 41 Kirochnaya Str. Tel.: +7 (921) 372-80-11. E-mail: jugrova@mail.ru. ORCID: 0000-0002-8622-5205
Вадим Иванович Мазуров, MD, professor, academician of RAS, head of the Department of therapy, rheumatology, examination of temporary disability and quality of medical care named after E.E. Eichwald, I.I. Mechnikov North-West State Medical University of the Ministry of Healthcare of Russia. Address: 191015, Saint Petersburg, 41 Kirochnaya Str. E-mail: maz.nwgmu@yandex.ru. ORCID: 0000-0001-8367-3144


Similar Articles


Бионика Медиа