A case of diagnostics of IgG4-related disease with primary renal damage and secondary arterial hypertension


DOI: https://dx.doi.org/10.18565/therapy.2022.1.102-109

Vladimirova N.N., Myasnikova E.V., Beketova T.V., Peredelkina A.I., Shunaev V.M., Pikunova I.N.

Central Clinical Hospital with Polyclinic of the Administration of the President of the Russian Federation, Moscow
Abstract. The article describes a clinical case of IgG4-associated disease diagnostics in a young patient with nephropathy and malignant hypertension. The analysis of the current state of the problem of IgG4-related diseases in the world is introduced. It deals with aspects of terminology, diagnostic criteria, pathogenesis and a variety of clinical manifestations, making difficult the detection of this pathology.

Literature



  1. Зыкова А.С., Новиков П.И., Бровко М.Ю. с соавт. IgG4-ассоциированное заболевание: что изменилось к 2020 году. Клиническая фармакология и терапия. 2020; 3: 4–13. [Zykova A.S., Novikov P.I., Brovko M.Yu. et al. IgG4-related disease: the state of art. Klinicheskaya farmakologiya i terapiya = Clinical Pharmacology and Therapy. 2020; 3: 4–13 (In Russ.)]. https://dx.doi.org/10.32756/0869-5490-2020-3-4-13.

  2. Maritati F., Peyronel F., Vaglio A. IgG4-related disease: A clinical perspective. Rheumatology (Oxford). 2020; 59(Suppl 3): iii123–iii131. https://dx.doi.org/10.1093/rheumatology/kez667.

  3. Zhang W., Stone J.H. Management of IgG4-related disease. Lancet Rheumatol. 2019; 1(1): E55–E65. https://dx.doi.org/10.1016/S2665-9913(19)30017-7.

  4. Kamisawa T., Funata N., Hayashi Y. et al. A new clinicopathological entity of IgG4-related autoimmune disease. J Gastroenterol. 2003;38(10): 982–84. https://dx.doi.org/10.1007/s00535-003-1175-y.

  5. Stone J.H., Khosroshahi A., Deshpande V. et al. Recommendations for the nomenclature of IgG4-related disease and its individual organ system manifestations. Arthritis Rheum. 2012; 64(10): 3061–67. https://dx.doi.org/10.1002/art.34593.

  6. Wallace Z.S., Zhang Y., Perugino C.A. et al. Clinical phenotypes of IgG4-related disease: An analysis of two international cross-sectional cohorts. Ann Rheum Dis. 2019; 78(3): 406–12. https://dx.doi.org/10.1136/annrheumdis-2018-214603.

  7. Wang M., Zhang P., Lin W. et al. Differences and similarities between IgG4-related disease with and without dacryoadenitis and sialoadenitis: Clinical manifestations and treatment efficacy. Arthritis Res Ther. 2019; 21(1): 44. https://dx.doi.org/10.1186/s13075-019-1828-8.

  8. Khosroshahi A., Wallace Z.S., Crowe J.L. et al. Second International Symposium on IgG4-Related Disease. International consensus guidance statement on the management and treatment of IgG4-related disease. Arthritis Rheumatol. 2015; 67(7): 1688–99. https://dx.doi.org/10.1002/art.39132.

  9. Wu Q., Chang J., Chen H. et al. Efficacy between high and medium doses of glucocorticoid therapy in remission induction of IgG4-related diseases: A preliminary randomized controlled trial. Int J Rheum Dis. 2017; 20(5): 639–46. https://dx.doi.org/10.1111/1756-185X.13088.

  10. Wang L., Zhang P., Wang M. et al. Failure of remission induction by glucocorticoids alone or in combination with immunosuppressive agents in IgG4-related disease: A prospective study of 215 patients. Arthritis Res Ther. 2018; 20(1): 65. https://dx.doi.org/10.1186/s13075-018-1567-2.


About the Autors


Nadezhda N. Vladimirova, PhD., cardiologist, Deputy chief physician for therapy of Central Clinical Hospital with Polyclinic of the Administration of the President of the Russian Federation. Address: 121359, Moscow, 15 Marshala Timoshenko Str. E-mail: glavchp@cchp.ru
Elena V. Myasnikova, therapist, head of the Department of Therapy No. 2, Central Clinical Hospital with Polyclinic of the Administration of the President of the Russian Federation. Address: 121359, Moscow, 15 Marshala Timoshenko Str. E-mail: dr.myasnikova@mail.ru
Tatyana V. Beketova, MD, rheumatologist, head of the Department of rheumatology, Central Clinical Hospital with Polyclinic of the Administration of the President of the Russian Federation. Address: 121359, Moscow, 15 Marshala Timoshenko Str.
Anna I. Peredelkina, cardiologist at Central Clinical Hospital with Polyclinic of the Administration of the President of the Russian Federation. Address: 121359, Moscow, 15 Marshala Timoshenko Str. E-mail: anik_lederep@bk.ru
Irina N. Pikunova, therapist at Central Clinical Hospital with Polyclinic of the Administration of the President of the Russian Federation. Address: 121359, Moscow, 15 Marshala Timoshenko Str.
Valentin M. Shunaev, therapist at Central Clinical Hospital with Polyclinic of the Administration of the President of the Russian Federation. Address: 121359, Moscow, 15 Marshala Timoshenko Str.


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