Ambroxol in the treatment of acute bronchitis and COVID-19


DOI: https://dx.doi.org/10.18565/therapy.2022.6.151-156

Alieva A.M., Batov M.A., Karabinenko A.A.

1) N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia, Moscow; 2) P.A. Herzen Moscow Scientific And Research Oncological Institute of Oncology – a branch of National Medical Research Radiological Centre of the Ministry of Healthcare of Russia
Abstract. Acute bronchitis (AB) is one of the most common conditions encountered in outpatient clinical practice. Before the COVID-19 pandemic, the U.S. Centers for Disease Control estimated that acute bronchitis accounted for about 10% of GP visits, or about 100 million visits per year. Ambroxol has mucokinetic and mucociliary effects that have been shown in clinical studies involving adult patients with respiratory disease, and therefore has potential for use in both OB and COVID-19. The aim of this review is to analyze clinical data on the use of ambroxol in actual medical practice in patients with AB. Comparatively convincing data on the effectiveness of ambroxol as a component of symptomatic and pathogenetic therapy of AB are presented. Studies on the efficacy of ambroxol administration in patients with COVID-19 have great prospects for introduction into clinical practice and are under active study.

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About the Autors


Amina M. Alieva, PhD in Medicine, associate professor of the Department of hospital therapy No. 2 of the Faculty of general medicine, N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia. Address: 117997, Moscow, 1 Ostrovityanova Str. E-mail: amisha_alieva@mail.ru. ORCID: https://orcid.org/0000-0001-5416-8579. SPIN-code: 2749-6427
Maxim A. Batov, resident doctor at P.A. Herzen Moscow Scientific and Research Oncological Institute of Oncology – a branch of National Medical Research Radiological Centre of the Ministry of Healthcare of Russia. Address: 125284, Moscow, 3 2nd Botkinsky Lane. E-mail: m.batov112@gmail.com. ORCID: https://orcid.org/0000-0002-3780-4358. SPIN-code: 5850-7711
Alexander A. Karabinenko, Dr. med. habil., professor of the Department of hospital therapy No. 2 of the Faculty of general medicine, N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia, therapist and pulmonologist of the highest category. Address: 117997, Moscow, 1 Ostrovityanova Str.


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