Русский
Assessment of the clinical course and outcomes of COVID-19 in vaccinated patients
DOI: https://dx.doi.org/10.18565/therapy.2022.8.48-53
Trofimov N.A., Tarasova L.V., Dimitrieva O.V., Babokin V.E., Dubova A.V.
1) I.N. Ulyanov Chuvash State University, Cheboksary; 2) Republican Cardiology Dispensary of the Ministry of Healthcare of the Chuvash Republic, Cheboksary; 3) Institute of Postgraduate Medical Education of the Ministry of Healthcare of the Chuvash Republic, Cheboksary; 4) Federal Center for Traumatology, Orthopedics and Arthroplasty of the Ministry of Healthcare of Russia (Cheboksary); 5) Privolzhsky Research Medical University, Nizhny Novgorod; 6) Surgut State University; 7) Republican Clinical Hospital of the Ministry of Healthcare of the Chuvash Republic, Cheboksary
Purpose: to assess the predictive value of vaccination in relation to the course of a novel coronavirus infection and its outcomes.
Material and methods. A comparative analysis of the clinical course and outcomes of COVID-19 was carried out among vaccinated (n=69) and unvaccinated patients (n=32) treated in the «Covid» hospital of the Republican Cardiology Dispensary of the Ministry of Healthcare of Chuvashia (RCD) from January to December 2021.
Results. Vaccinated patients were less likely to be hospitalized in RCD, which indicates a more favorable course of COVID-19 in vaccinated patients. Unvaccinated patients were 2,5 times more likely to be admitted to the intensive care unit (ICU) and 3,8 times more likely to die at the hospital stage.
Conclusion. Vaccination against COVID-19 does not exclude infection with a new coronavirus infection, but significantly reduces the risk of a severe course of a new coronavirus infection, admission to a hospital, intensive care unit, and, most importantly, significantly reduces the risk of death.
Literature
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About the Autors
Nikolai A. Trofimov, Dr. med. habil., associate professor of the Department of surgical diseases and general surgery, I.N. Ulyanov Chuvash State University, professor of the Department of surgery, Institute of Postgraduate Medical Education of the Ministry of Healthcare of the Chuvash Republic, deputy chief physician for surgery of Republican Cardiology Dispensary of the Ministry of Healthcare of the Chuvash Republic. Address: 428000, Cheboksary, 29а Fedora Gladkova Str. E-mail: nikolai.trofimov@mail.ru. ORCID: https://orcid.org/0000-0002-1975-5521
Larisa V. Tarasova, Dr. med. habil., head of the Department of faculty and hospital therapy, I.N. Ulyanov Chuvash State University, professor of the Department of internal diseases, Medical Institute of Surgut State University, professor of the Department of public health and healthcare, Institute of Postgraduate Medical Education of the Ministry of Healthcare of the Chuvash Republic. Address: 428015, Cheboksary, 45 Moskovsky Avenue. E-mail: tlarisagast18@mail.ru. ORCID: https://orcid.org/0000-0003-1496-0689
Olga V. Dimitrieva, assistant at the Department of faculty and hospital therapy, I.N. Ulyanov Chuvash State University, head of the Department of quality control and safety of medical activities, Republican Cardiology Dispensary of the Ministry of Healthcare of the Chuvash Republic. Address: 428000, Cheboksary, 29а Fedora Gladkova Str. E-mail: salgarii@mail.ru. ORCID: https://orcid.org/0000-0002-7771-6141
Vadim E. Babokin, Dr. med. habil., head of the Department of surgical diseases, I.N. Ulyanov Chuvash State University, professor of the Department of surgery, Institute of Postgraduate Medical Education of the Ministry of Healthcare of the Chuvash Republic, chief physician for surgery of Republican Cardiology Dispensary of the Ministry of Healthcare of the Chuvash Republic. Address: 428000, Cheboksary, 29а Fedora Gladkova Str. E-mail: babokin@bk.ru. ORCID: https://orcid.org/0000-0002-2788-8762
Alexandra Vю Dubova, PhD in Medicine, associate professor of the Department of faculty and hospital therapy, I.N. Ulyanov Chuvash State University, deputy chief medical officer of Republican Cardiology Dispensary of the Ministry of Healthcare of the Chuvash Republic. Address: 428000, Cheboksary, 29а Fedora Gladkova Str. E-mail: dubova-sasha@mail.ru. ORCID: https://orcid.org/0000-0002-9732-6343
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