Primary immune deficiency disease in adults. Preferential disturbance of antibody synthesis


DOI: https://dx.doi.org/10.18565/therapy.2018.7-8.119-124

E.A. Latysheva

«Institute of Immunology» FSBI State Scientific Center of FMBA of Russia
The problem of primary immunodeficiency (PID) in adults becomes more and more important in recent years, as the number of such kind of patients over 18 years of age has been steadily increasing; the number of them amounts to 30–40% of PID registers in different countries. Due to low awareness of this group of diseases, they are characterized by low detectability and late diagnosis. The article discusses the most common forms of PID which are character for persons over 18 years old, also the actual aspects of clinic, diagnosis and treatment are represented.
Keywords: primary immunodeficiency in adults, general variable immune deficiency, selective IgA deficiency, deficiency of IgG subclasses, X-lined immunoglobulinemia, immunoglobulins
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    • About the Autors

    Elena A. Latysheva, PhD, associate professor of the Department of clinical immunology of «N.I. Pirogov RNRMU» FSBEI of HE, Senior research scientist of the Department of immunopathology of the Institute Of Immunology clinic Federal state budgetary institution MRI of FMBA of Russia. Address: 115478, Moscow, 24 Kashirskoye shosse St. Tel: +74996127773. E-mail: ea.latysheva@nrcii.ru

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