Algorithms of antithrombotic therapy of patients in the perioperative period: what should a clinican knows?


DOI: https://dx.doi.org/10.18565/therapy.2020.5.157-162

Kotova D.P., Shemenkova V.S.

1) City clinical hospital №1 named after N.I. Pirogov of the Department of Healthcare of Moscow; 2) N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia, Moscow
The development of modern medicine leads to an increasing number of surgical interventions, including in the elderly and patients with severe comorbidities. In this regard, a doctor of any specialty often faces the question of the need for planned surgical treatment in patients receiving anticoagulants and disaggregants. Perioperative management of this category of patients is a rather complex problem, since taking antithrombotic drugs increases the risk of bleeding during surgery and their cancellation in the presence of certain comorbidities may lead to thromboembolic complications. This article covers the issues of prescribing and interrupting long-term anticoagulant and disaggregant therapy when planning surgery and conducting regional anesthesia. The purpose of this review is to determine possible schemes for prescribing antithrombotic drugs in the perioperative period to reduce the risk of possible bleeding and maintain thromboembolic prevention.
Keywords: anticoagulants in surgery, antithrombotic therapy, bridge therapy, thromboembolic complications
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About the Autors

Daria P. Kotova, PhD, head of the therapeutic department of City clinical hospital №1 named after N.I. Pirogov of the Department of Healthcare of Moscow, associate professor of the Department of faculty therapy of N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia. Address: 119049, Moscow, 10/5 Leninsky Prospect. Tel.: +7 (905) 539-36-36. E-mail: doc.kotova@mail.ru
Victoria S. Shemenkova, therapist of City clinical hospital №1 named after N.I. Pirogov of the Department of Healthcare of Moscow, senior laboratory assistant of the Department of faculty therapy of N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia. Address: 119049, Moscow, 10/5 Leninsky Prospect.
Tel.: +7 (915) 319-55-35. E-mail: vshemenkova@mail.ru

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