Anemia in acute coronary syndrome: prognostic value and treatment


DOI: https://dx.doi.org/10.18565/therapy.2021.3.74-79

Morozova V.D., Glushakov I.A., Kalyuta T. Yu., Posnenkova O.M., Zheleznyakova N.A., Kiselev A.R., Schwartz Yu.G., Gridnev V.I.

1) V.I. Razumovsky Saratov State Medical University of the Ministry of Healthcare of Russia; 2) National Medical Research Center for Therapy and Preventive Medicine of the Ministry of Healthcare of Russia, Moscow
Abstract. The article reviews the data on anemia impact in acute coronary syndrome (ACS) course, prognosis, and approaches to the treatment of ACS regarding presence of anemia and correction of anemia in ACS patients. Elibrary and PubMed databases were analyzed in the period since 2015 till 2020 as well as the most recent Russian and European clinical guidelines on acute coronary syndrome. Anemia has been shown to have a significant negative impact on short-and long-term outcomes in patients with acute forms of coronary artery disease. Revascularization is rarely prescribed to patients with ACS accompanied by anemia. Such patients are rarely prescribed standard medical therapy for ACS. Therapeutic options for the treatment of anemia in ACS remain limited. The aspects of dual antiplatelet therapy prescription and revascularization options in ACS patients with anemia have not been sufficiently studied.
Keywords: anemia, acute coronary syndrome, prognostic value, treatment
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About the Autors

Victoria D. Morozova, 4th year student of Faculty of pediatrics, V.I. Razumovsky Saratov State Medical University of the Ministry of Healthcare of Russia. Address: 410012, Saratov, 112 Bol`shaya Kazach`ya Str. Tel.: +7 (917) 328-36-62. E-mail: viktoriya.morozova64@yandex.ru. ORCID: 0000-0003-4144-1550
Igor A. Glushakov, 4th year student of Faculty of pediatrics, V.I. Razumovsky Saratov State Medical University of the Ministry of Healthcare of Russia. Address: 410012, Saratov, 112 Bol`shaya Kazach`ya Str. Tel.: +7 (902) 048-86-32. E-mail: igor1699@mail.ru. ORCID: 0000-0002-3075-9910
Tatiana Yu. Kalyuta, PhD, senior researcher of the Department of preventive cardiology and rehabilitation, Research Institute of Cardiology of V.I. Razumovsky Saratov State Medical University of the Ministry of Healthcare of Russia. Address: 410012, Saratov, 112 Bol`shaya Kazach`ya Str. Tel.: +7 (905) 386-71-23. E-mail: tatianakaluta@yandex.ru. ORCID: 0000-0003-3172-0804
Olga M. Posnenkova, MD, head of the Department of atherosclerosis and chronic coronary artery disease, Research Institute of Cardiology of V.I. Razumovsky Saratov State Medical University of the Ministry of Healthcare of Russia. Address: 410012, Saratov, 112 Bol`shaya Kazach`ya Str. Tel.: +7 (905) 380-39-07. E-mail: posnenkova@cardio-it.ru. ORCID: 0000-0001-5311-005X
Natalia A. Zheleznyakova, PhD, senior researcher of the Department of preventive cardiology and rehabilitation of Research Institute of Cardiology, assistant of the Department of faculty therapy, Faculty of general medicine of V.I. Razumovsky Saratov State Medical University of the Ministry of Healthcare of Russia. Address: 410012, Saratov, 112 Bol`shaya Kazach`ya Str. Tel.: +7 (906) 316-95-98. E-mail: natzheleznyakova@yandex.ru. ORCID: 0000-0002-7890-8305
Anton R. Kiselev, MD, associate professor, head of the Department of novel cardiology information technology, Research Institute of Cardiology of V.I. Razumovsky Saratov State Medical University of the Ministry of Healthcare of Russia, head of Coordinating Center for Fundamental Research, National Medical Research Center for Therapy and Preventive Medicine of the Ministry of Healthcare of Russia. Address: 410012, Saratov, 112 Bol`shaya Kazach`ya Str. Tel.: +7 (906) 312-22-16. E-mail: antonkis@list.ru. ORCID: 0000-0003-3967-3950
Yuri G. Schwartz, MD, professor, Director of the Faculty Therapy Clinic, head of Department of faculty therapy, V.I. Razumovsky Saratov State Medical University of the Ministry of Healthcare of Russia. Address: 410012, Saratov, 112 Bol`shaya Kazach`ya Str. Tel.: +7 (927) 220-11-01. E-mail: shwartz58@yandex.ru. ORCID: 0000-002-5205-7311
Vladimir I. Gridnev, MD, associate professor, Director of the Research Institute of Cardiology of V.I. Razumovsky Saratov State Medical University of the Ministry of Healthcare of Russia. Address: 410012, Saratov, 112 Bol`shaya Kazach`ya Str. Tel.: +7 (8452) 39-39-78. E-mail: gridnev@cardio-it.ru. ORCID: 0000-0001-6807-7934

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