Tick-borne encephalitis in the Tomsk region


DOI: https://dx.doi.org/10.18565/therapy.2021.5.14-21

Zhukova N.G., Poltoratskaya T.N., Sizova N.N., Poltoratskaya N.V., Pankina T.M., Shikhin A.V., Rudikov A.A., Obukhova V.S., Zhukova I.A.

1) Siberian State Medical University of the Ministry of Healthcare of Russia, Tomsk; 2) Center of Hygiene and Epidemiology in the Tomsk region, Tomsk; 3) Department of Rospotrebnadzor for the Tomsk region, Tomsk
Abstract. Purpose: to characterize the epidemiological features of tick-borne encephalitis (TBE) in the Tomsk region in 2000–2020 and to analyze measures to prevent the incidence of TBE.
Material and methods. The data of epidemiological monitoring (statistical forms No. 1, 2, 5) for TBE in the Tomsk region from 2000 to 2020, the results of clinical examinations of hospitalized patients with TBE and outpatient records of patients with TBE from 2000 to 2020 in the Tomsk region were used.
Results. During the analyzed period, 4,726 cases of TBE were registered, including 30 cases with a fatal outcome. In the Tomsk region in the epidemiological seasons of 2000–2020, 1 143 922 people were covered by vaccination, of which 360 (0,03%) subsequently became ill. The immune stratum of the population for the analyzed period averaged only 19,2±4,7%. During the same period, 82066 patients received immunoglobulin only after a positive result of a tick or blood test, of which 926 (1,1%) patients became ill. Prevention with Iodantipyrin was carried out in 19 734 patients, of whom 108 (0,5%) people became ill.
Conclusions. In the Tomsk region, in recent years, there has been a steady trend towards a decrease in the incidence of TBE, there is a «rejuvenation» and an increase in the incidence among infected older age groups. The prevalence of male TBE virus deaths remains high. The meningoencephalitic form of TBE prevailed among the dead. Currently, the system of prevention of the disease of TBE includes vaccination, emergency (immunoglobulin) and chemoprophylaxis. During the analyzed period, the majority (80,8±4,7%) of the population were unvaccinated residents of the region.
Keywords: prevention of tick-borne encephalitis, outcomes of tick-borne encephalitis, immunoglobulin, tick-borne encephalitis
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About the Autors

Natalia G. Zhukova, MD, professor, professor of the Department of neurology and neurosurgery, Siberian State Medical University of the Ministry of Healthcare of Russia. Address: 634050, Tomsk, 2 Moskovsky tract. Tel.: +7 (913) 824-62-02. E-mail: znatali@yandex.ru. ORCID: 0000-0001-6547-6622
Tatiana N. Poltoratskaya, PhD, head of the Laboratory of parasitological research, Center of Hygiene and Epidemiology in the Tomsk region. Address: 634009, Tomsk, 13a R. Luxemburg Str. Tel.: +7 (906) 949-18-87. E-mail: parsesto@mail.tomsknet.ru
Natalia N. Sizova, Doctor of clinical laboratory diagnostics of the Laboratory of parasitological research, Center of Hygiene and Epidemiology in the Tomsk region. Address: 634009, Tomsk, 13a R. Luxemburg Str. Tel.: +7 (913) 870-93-88. E-mail: parsesto@mail.tomsknet.ru
Natalia V. Poltoratskaya, PhD, entomologist of parasitological research of Center of Hygiene and Epidemiology in the Tomsk region. Address: 634009, Tomsk, 13a R. Luxemburg Str. Tel.: +7 (913) 879-09-18. E-mail: parsesto@mail.tomsknet.ru
Tatiana M. Pankina, entomologist of parasitological research of Center of Hygiene and Epidemiology in the Tomsk region. Address: 634009, Tomsk, 13a R. Luxemburg Str. Tel.: +7 (905) 992-41-62. E-mail: parsesto@mail.tomsknet.ru
Alexander V. Shikhin, PhD, Chief physician of Center of Hygiene and Epidemiology in the Tomsk region. Address: 634012, Tomsk, 42 Elizarovykh Str. Tel.: +7 (3822) 54-09-27. E-mail: tcgsen@mail.tomsknet.ru
Andrey A. Rudikov, head of the Department of epidemiological surveillance, Department of Rospotrebnadzor for the Tomsk region. Address: 634021, Tomsk, 103а Frunze Avenue. Tel.: +7 (3822) 26-03-90. E-mail: dr.rudikov@mail.ru
Varvara S. Obukhova, 4th year student of the Faculty of general medicine, Siberian State Medical University of the Ministry of Healthcare of Russia. Address: 634050, Tomsk, 2 Moskovsky tract. Tel.: +7 (913) 800-96-02. E-mail: varvaraobukhova@yandex.ru. ORCID: 0000-0001-6141-123
Irina A. Zhukova, PhD, associate professor of the Department of neurology and neurosurgery, Siberian State Medical University of the Ministry of Healthcare of Russia. Address: 634050, Tomsk, 2 Moskovsky tract. Tel.: +7 (913) 800-62-96. E-mail: znatali@yandex.ru. ORCID: 0000-0001-5679-1698

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