Modern strategy of diagnosis and therapy of patients with obstructive sleep apnea


DOI: https://dx.doi.org/10.18565/therapy.2021.8.144-150

Babak S.L., Budnevsky A.V., Buzunov R.V.

1) A.I. Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Healthcare of Russia; 2) N.N. Burdenko Voronezh State Medical University of the Ministry of Healthcare of Russia; 3) Central State Medical Academy of the Administrative Department of the President of the Russian Federation, Moscow
Abstract. Obstructive sleep apnea (OSA), as a heterogeneous chronic disease, significantly reduces the quality of life, aggravates the course of comorbidities and increases the mortality of patients from all causes. Choosing an effective therapy for OSA patients will require a comprehensive assessment of therapeutic and minimally invasive surgical interventions. At the same time, the multidisciplinary approach to the treatment of OSA patients involving a variety of clinical strategies, is poorly understood from the standpoint of evidence-based medicine. Most scientific publications on this topic are not randomized controlled trials, which makes it difficult to assess their applicability in real clinical practice. In this article, the authors provide a brief overview of modern effective and justified diagnostic and therapeutic interventions that allow clinician to form a personalized strategy for the diagnosis and treatment of comorbid OSA patients in accordance with the principles of precision medicine.
Keywords: OSA, precision medicine, multidisciplinary approach, minimally invasive surgery, evidence-based medicine, obstructive sleep apnea
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About the Autors

Sergey L. Babak, MD, professor of the Department of phthisiology and pulmonology of the Faculty of general medicine, A.I. Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Healthcare of Russia. Address: 107150, Moscow, 39/2 Losinoostrovskaya Str. E-mail: sergbabak@mail.ru. ORCID: 0000-0002-6571-1220. Scopus Author ID: 45560913500
Andrey V. Budnevsky, MD, professor, head of the Department of faculty therapy, N.N. Burdenko Voronezh State Medical University of the Ministry of Healthcare of Russia of the Ministry of Healthcare of Russia. Address: 394036, Voronezh, 10 Studencheskaya Str. E-mail: budnev@list.ru. ORCID: orcid.org/0000-0002-1171-2746.
Roman V. Buzunov, MD, professor of the Department of family medicine with courses in clinical laboratory diagnostics, psychiatry and psychotherapy, Central State Medical Academy of the Administrative Department of the President of the Russian Federation, Honored Doctor of the Russian Federation. Address: 121359, Moscow, 19/1А Marshala Timoshenko Str. E-mail: 7633331@mail.ru


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