Atypical celiac disease with late onset, damage of gastrointestinal tract, nervous and musculoskeletal systems of the organism


DOI: https://dx.doi.org/10.18565/therapy.2021.10.121-126

Gaydukova I.Z., Mazurov V.I., Pilipenko A.I.

1) I.I. Mechnikov North-Western State Medical University of the Ministry of Healthcare of Russia, Saint Petersburg; 2) City Polyclinic No.19, Saint Petersburg
Abstract. The most typical manifestations of celiac disease are gastrointestinal symptoms. At the same time, in some patients, extraintestinal manifestations of the disease come at the first line. The aim of the presented work is to describe a case of atypical celiac disease in a female patient born in 1978 with a late onset (at age 37), damages of musculoskeletal system and nervous system. Presented data allow us to conclude that the diagnosis and treatment of celiac disease can cause difficulties in case of the late onset of the disease and predominance of extraintestinal symptoms (damage of nervous and/or musculoskeletal systems). Currently, the only treatment for intestinal and extraintestinal symptoms of celiac disease is a gluten-free diet, which can lead to remission even in the case of the most severe disease course.
Keywords: arthritis in celiac disease, gluten enteropathy, extraintestinal manifestations of celiac disease, atypical celiac disease
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About the Autors

Inna Z. Gaydukova, MD, Deputy Director of the Research Institute of Rheumatology, I.I. Mechnikov North-Western State Medical University of the Ministry of Healthcare of Russia, professor of the Department of therapy, rheumatology, expertise of temporary disability and medical care quality named after E.E. Eichwald, I.I. Mechnikov North-Western State Medical University of the Ministry of Healthcare of Russia. Address: 191015, Saint Petersburg, 41 Kirochnaya Str. Tel.: +7 (903) 329-03-59. E-mail: ubp1976@list.ru. ORCID: 0000-0003-3500-7256. SPIN-code: 3083-7996
Vadim I. Mazurov, MD, professor, academician of RAS, honored scientist of the Russian Federation, Chief scientific consultant, Director of the Research Institute of Rheumatology, I.I. Mechnikov North-Western State Medical University of the Ministry of Healthcare of Russia, head of the Department of therapy, rheumatology, expertise of temporary disability and medical care quality named after E.E. Eichwald, I.I. Mechnikov North-Western State Medical University of the Ministry of Healthcare of Russia, head of the Center for autoimmune diseases, Clinical Rheumatological Hospital No. 25. Address: 191015, Saint Petersburg, 41 Kirochnaya Str. E-mail: maz.nwgmu@yandex.ru. ORCID: 0000-0002-0797-2051. SPIN-code: 6823-5482
Anastasia I. Pilipenko, rheumatologist at City Polyclinic No.19 (Saint Petersburg). Address: 192238, Saint Petersburg, 11 Prazhskaya Str. E-mail: anastasiyamoderova@gmail.com

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