Federal clinical recommendations for sarcoidosis diagnosis and treatment: Accents and comments


DOI: https://dx.doi.org/10.18565/therapy.2023.6.38-48

Vizel A.A., Avdeev S.N., Malyavin A.G., Shmelev E.I., Vizel I.Yu.

1) Kazan State Medical University of the Ministry of Healthcare of Russia; 2) N.V. Sklifosovsky Institute of Clinical Medicine of I.M. Sechenov First Moscow State Medical University of the Ministry of Healthcare of Russia (Sechenov University); 3) Research Institute of Pulmonology of FMBA, Moscow; 4) Moscow State University of Medicine and Dentistry of the Ministry of Healthcare of Russia; 5) Central Research Institute of Tuberculosis, Moscow
Abstract. Sarcoidosis is a multi-organ granulomatosis of unknown origin. Diagnosis and treatment of this disease have not been unified for a long time. In 2022, many authors from three scientific medical communities presented federal clinical guidelines on sarcoidosis, which were approved by the Ministry of Healthcare of Russia in the same year. Current article contains the most important practical aspects of this disease, which include the absence of specific markers, need to compare radiation, clinical, morphological and functional data, the presence of variants of clinical course of sarcoidosis without respiratory damage. It is extremely important for physicians to know and understand when and how to start treatment of sarcoidosis, how to manage patients, avoiding early prescription of hormones and cytostatics and responding in a timely manner to the progression of the disease and the development of life-threatening conditions.
Keywords: treatment of sarcoidosis, clinical manifestations of sarcoidosis, diagnosis of sarcoidosis, sarcoidosis
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Literature

1. Саркоидоз. Монография. Под ред. А.А. Визеля (серия монографий Российского респираторного общества; гл. ред. серии – А.Г. Чучалин). М.: Издательский холдинг «Атмосфера». 2010; 416 с. [Sarcoidosis. Monograph. Ed. by Wiesel A.A. (a series of monographs of the Russian Respiratory Society; chief editor of the series – Chuchalin A.G.). Moscow: Publishing holding «Atmosfera”. 2010; 416 pp. (In Russ.)]. ISBN: 978-5-902123-34-7.


2. Клинические рекомендации. Саркоидоз. Российское респираторное общество, общероссийская общественная организация «Российское научное медицинское общество терапевтов», общероссийская общественная организация «Педиатрическое респираторное общество». Рубрикатор клинических рекомендаций Минздрава России. 2022. ID: 736. Доступ: https://cr.minzdrav.gov.ru/schema/736_1 (дата обращения – 01.08.2023). [Clinical guidelines. Sarcoidosis. Russian Respiratory Society, Russian Scientific Medical Society of Internal Medicine, Pediatric Respiratory Society. Rubricator of clinical guidelines of the Ministry of Healthcare of Russia. 2022. ID: 736. URL: https://cr.minzdrav.gov.ru/schema/736_1 (date of access – 01.08.2023) (In Russ.)].


About the Autors

Alexander A. Vizel, MD, professor, head of the Department of phthisiology and pulmonology, Kazan State Medical University of the Ministry of Healthcare of Russia. Address: 420012, Kazan, 49 Butlerova Str. E-mail: lordara@inbox.ru. ORCID: https://orcid.org/0000-0001-5028-5276. SPIN code: 5918-5465; Author ID: 195447
Sergey N. Avdeev, MD, professor, academician of RAS, head of the Department of pulmonology of N.V. Sklifosovsky Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University of the Ministry of Healthcare of Russia (Sechenov University), leading researcher at Research Institute of Pulmonology of FMBA. Address: 107045, Moscow, 3 Bolshaya Sukharevskaya Sq. E-mail: serg_avdeev@list.ru.
ORCID: https://orcid.org/0000-0002-5999-2150. SPIN-code: 1645-5524
Andrey G. Malyavin, MD, professor, professor of the Department of phthisiology and pulmonology, Moscow State University of Medicine and Dentistry of the Ministry of Healthcare of Russia. Address: 107150, Moscow, 39/1 Losinoosyrovskaya Str. E-mail: maliavin@mail.ru. ORCID: https://orcid.org/0000-0002-6128-5914
Evgeny I. Shmelev, MD, professor, head of the Department of differential diagnostics, Central Research Institute of Tuberculosis. Address: 107564, Moscow, 2 Yauzskaya alley. E-mail: eishmelev@mail.ru.
ORCID: http://orcid.org/000-002-1908-5601
Irina Yu. Vizel, MD, professor of the Russian Academy of Natural Sciences, associate professor of the Department of phthisiology and pulmonology, Kazan State Medical University of the Ministry of Healthcare of Russia. Address: 420012, Kazan, 49 Butlerova Str. E-mail: tatpulmo@mail.ru. ORCID: https://orcid.org/0000-0002-8855-8177


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