Features of reflux esophagitis in patients with gastroesophageal reflux disease combined with diabetes mellitus 1 and 2 type


Z.K. Basieva, E.A. Shavlokhova, E.V. Mulukhova, A.Yu. Kekhoeva

1 Federal State Budgetary Educational Institution of Higher Education “North Osetian state medical academy” of the Ministry of Healthcare of Russia, Vladikavkaz; 2 Republican endocrinology dispensary, Republic of North Ossetia - Alania, Vladikavkaz
The study presents the results of examination of 31 patients with gastroesophageal reflux disease in combination with type 1 diabetes and 82 patients with gastroesophageal reflux disease in combination with type 2 diabetes. The control group consisted of 32 patients with GERD without concomitant diabetes. The groups were matched for age. All patients underwent 24 - hour esophageal pH-metry and esophagogastroduodenoscopy, then subgroups were formed depending on the type and severity of diabetes in order to study the frequency of gastroesophageal reflux (GER) in patients with comorbidities. After analyzing the results, it was found that in patients with concomitant diabetes mellitus gastroesophageal reflux was more pronounced and prolonged in comparison with the control group. The maximum duration of GER was in patients with diabetes type 2 diabetes. In these patients, the highest percentage of endoscopy revealed lesions of the mucous distal esophageal (75.6%), which indirectly indicates a more severe course of GERD in patients with type 2 diabetes.
Keywords: pH-metry of esophagus esophagogastroduodenoscopy, gastroesophageal reflux, diabetes
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Literature

  • Лазебник Л.Б., Машарова А.А., Васнев О.С., Бордин Д.С, Валитова Э.Р., Янова О.Б. Гастроэзофагеальная рефлюксная болезнь у пожилых: эпидемиология, клиника, лечение // Экспериментальная и клиническая гастроэнтерология. 2010. № 12. С. 10–16. [Lazebnik L.B., Masharova A.A., Vasnev O.S., Bordin D.S., Valigova Ae.R., Yanova O.B. Gastroesophageal reflux disease in elderly patients: epidemiology, clinical course, treatment // experimental and clinical gastroenterology. 2010. № 12. P. 10–16.]
  • Алгоритмы специализированной медицинской помощи больным сахарным диабетом / Под ред. / И.И. Дедова, М.В. Шестаковой, А.Ю. Майорова. 8-й выпуск. М.: УП ПРИНТ; 2017. С. 1–122. [Algorythms of specialized medical care for diabetes melitus patients./ Under the edition of I.I. Dedova, M.V. Shestakova, A.Ju. Maiorova - 8th edition. M.:UP PRINT;2017. P.1–122.]
  • Жукова Т.В. Гастроэзофагеальная рефлюксная болезнь в практике врача-терапевта Медицинские новости. 2017. № 8. С. 39–41. [Zhukova T.V. Gastroesophageal reflux disease in the practice of physician. Medical news. 2017. № 8. P. 39–41.]
  • Ивашкин В.Т., Маев И.В., Трухманов А.С. и др. / Гастроэзофагеальная рефлюксная болезнь. Клинические рекомендации / Российская гастроэнтерологическая ассоциация. М., 2014. С. 1–23. [Ivashkin V.T., Maev I.V., Trukhmanov A.S. and others./Gastroesophageal reflux disease. Clinical recommendations. Russian association of gastroenterology. M., 2014 P. 1–23.]
  • Кокина Н.И. Особенности клиники, диагностики и лечения рефлюксной болезни пищевода, сочетающейся с сахарным диабетом. Автореф. дис. … канд. мед. наук. М., 1998. С. 1–20. [Kokina N.I./ Peculiarities of clinic, diagnostics and treatment of reflux disease of esophagus in combination with diabetes melitus. / Abstract of the diss.of cand.of med.sciences. M.,1998. С. 1–20.]
  • Корнеева Н.В., Федорченко Ю.Л. Особенности клиники и течения гастроэзофагеальной рефлюксной болезни у больных сахарным диабетом /Сахарный диабет. 2011. № 4. С. 71–74. [Korneeva N.V., Fedorchenko Ju.L./ Peculiarities of clinic and clinicall course of gastroesophageal reflux disease in diabetes melitus patients. / Diabetes melitus., 2011. № 4. P. 71–74.]
  • Пахомова И.Г., Зиновьева Е.Н. Гастроэзофагеальная рефлюксная болезнь у полиморбидного пациента: особенности терапии. «РМЖ»., 2017. № 10. С. 760–764. [Pakhomova I.G., Zinovieva E.N. Gastroesophageal reflux disease in polymorbid patient: peculiarities of therapy. “RMJ” 2017.- № 10. P. 760–764.]
  • Тарасенко Н.А. Сахарный диабет: действительность, прогнозы, профилактика / Современные проблемы науки и образования., 2017. № 6.; URL: http://science-education.ru/ru/article/viewid=27144 [Tarasenko N.A. / Diabetes melitus: reality, prognostications, prevention. / Modern problems of science and education., 2017.– № 6.; URL: http://science-education.ru/ru/article/viewid=27144]


    • About the Autors

    Zarina K. Basieva, PhD., assistant of the Department of the internal medicine № 2 of Federal State Budgetary Educational Institution of Higher Education “North Ossetian state medical academy” of the Ministry of Healthcare of Russia, Vladikavkaz. Address: 362019, RSO-Alania, Vladikavkaz, 40 Pushkinskaya Str. E-mail: sogma.rso@gmail.com

    Emma A. Shavlokhova, PhD., associate professor of the Department of the internal medicine № 2 of Federal State Budgetary Educational Institution of Higher Education “North Ossetian state medical academy” of the Ministry of Healthcare of Russia. Republican endocrinologic dispensary. RSO-Alania, Vladikavkaz. E-mail: emma651@yandex.ru

    Elda V. Mulukhova, PhD, assistant of the Department of the internal medicine № 2 of Federal State Budgetary Educational Institution of Higher Education “North Ossetian state medical academy” of the Ministry of Healthcare of Russia, Vladikavkaz

    Alyona. Ju. Kekhoeva, PhD., assistant of the Department of the internal medicine № 2 of Federal State Budgetary Educational Institution of Higher Education “North Ossetian state medical academy” of the Ministry of Healthcare of Russia, Vladikavkaz


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