Rheumatological «masks» of hyperparathyroidism: focus on the disease of deposition of calcium pyrophosphate crystals


DOI: https://dx.doi.org/10.18565/therapy.2022.7.78-84

Bashkova I.B., Madyanov I.V.

1) I.N. Ulyanov Chuvash State University, Cheboksary; 2) Federal Center of Traumatology, Orthopedics and Arthroplasty of the Ministry of Healthcare of Russia, Cheboksary; 3) Institute of Postgraduate Medical Education of the Ministry of Healthcare of the Chuvash Republic, Cheboksary
Abstract. Hyperparathyroidism is one of the most common endocrine diseases, known for a variety of clinical manifestations, including simulating rheumatological diseases. The article analyzes a clinical case in which a 65-year-old patient with articular syndrome was consistently diagnosed with rheumatoid arthritis as the main one, then with calcium pyrophosphate crystal deposition disease, and as a result it turned out that the most obvious cause of all clinical manifestations in this case was hyperparathyroidism due to the development of parathyroid adenoma. According to the authors, the reasons for the late diagnosis of hyperparathyroidism in this clinical observation were insufficient awareness of doctors about this pathology and its clinical manifestations, as well as underestimation of the importance of determining and accounting for the concentration of calcium in the blood in articular pathology. In particular, in the analyzed case, due attention was not paid to hypercalcemia, recorded long before the diagnosis of parathyroid adenoma.
Keywords: calcium pyrophosphate crystal deposition disease, parathyroid adenoma, hypercalcemia, hyperparathyroidism, rheumatoid arthritis
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About the Autors

Inna B. Bashkova, PhD in Medicine, associate professor, associate professor of the Department of faculty and hospital therapy, I.N. Ulyanov Chuvash State University, rheumatologist at consultative polyclinic of Federal Center for Traumatology, Orthopedics and Arthroplasty of the Ministry of Healthcare of Russia. Address: 428015, Cheboksary, 15 Moskovsky Avenue. E-mail: innabashkova@yandex.ru. ORCID: https://orcid.org/0000-0003-3509-1072
Igor V. Madyanov, Dr. med. habil., professor, professor of the Department of faculty and hospital therapy, I.N. Ulyanov Chuvash State University, professor of the Department of therapy and family medicine, Institute of Postgraduate Medical Education of the Ministry of Healthcare of the Chuvash Republic. Address: 428015, Cheboksary, 15 Moskovsky Avenue. E-mail: igo-madyanov@yandex.ru. ORCID: https://orcid.org/0000-0001-8750-2799


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