Sarcopenia: Aspects of diagnosis and prevention


DOI: https://dx.doi.org/10.18565/therapy.2024.1.74-84

Dobrovolskaya O.V., Feklistov A.Yu., Toroptsova N.V.

V.A. Nasonova Research Institute of Rheumatology, Moscow
Abstract. Sarcopenia (SP) is a multi-etiological syndrome manifested by a progressive loss of muscle strength and mass. It occurs either secondary to the natural degenerative processes, or as a complication of various chronic diseases, worsening the course and prognosis of them. SP presence increases the risk of falls and fractures, leads to decrease of life quality and negatively affects its duration. Current review presents modern data on the mechanisms of the occurrence and development of muscle weakness, also a diagnostic algorithm and possible methods for SP prevention.

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About the Autors


Olga V. Dobrovolskaya, MD, PhD (Medicine), researcher at the Department of osteoporosis, V.A. Nasonova Research Institute of Rheumatology. Address: 115522, Moscow, 34a Kashirskoe Highway.
E-mail: epid@irramn.ru
ORCID: https://orcid.org/0000-0002-2809-0197
Alexey Yu. Feklistov, MD, rheumatologist at V.A. Nasonova Research Institute of Rheumatology. Address: 115522, Moscow, 34a Kashirskoe Highway.
E-mail: epid@irramn.ru
ORCID: https://orcid.org/0000-0002-7661-3124
Natalya V. Toroptsova, MD, Dr. Sci. (Medicine), head of the Department of osteoporosis, V.A. Nasonova Research Institute of Rheumatology. Address: 115522, Moscow, 34a Kashirskoe Highway.
E-mail: torop@irramn.ru
ORCID: https://orcid.org/0000-0003-4739-4302


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