Exocrine pancreatic insufficiency – behind the veil of chronic pancreatitis and more. Part 2: Modern approaches to diagnosis and treatment


DOI: https://dx.doi.org/10.18565/therapy.2025.1.150-159

Mironchev A.O., Isaev M.R., Mironchev O.V.

Orenburg State Medical University of the Ministry of Healthcare of Russia
Abstract. Exocrine pancreatic insufficiency (EPI) is a pathological condition that develops as a result of both chronic pancreatitis and other diseases discussed in the first part of the lecture. EPI invariably leads to progressive digestion disorders, and with a long history of the disease – to disorders of absorption of nutrients, vitamins and microelements in the intestine, which, in turn, entails trophological insufficiency and a number of other disorders in various organs and systems. Despite the typical clinical picture, the disease often goes undiagnosed by practicing physicians, and patients do not receive adequate treatment. The aim of the article is to analyze, from the standpoint of evidence-based medicine, the modern principles of diagnosis and treatment of EPI, knowledge of which is necessary in the daily work of a general practitioner.

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About the Autors


Anton O. Mironchev, MD, PhD (Medicine), dean of the Faculty for foreign students, acting head of the Department of clinical medicine, Institute of Professional Education of Orenburg State Medical University of the Ministry of Healthcare of Russia. Address: 460014, Orenburg, 6 Sovetskaya St.
E-mail: Antomirr@mail.ru
Marat R. Isaev, MD, PhD (Medicine), associate professor, associate professor of the Department of clinical medicine, Institute of Professional Education of Orenburg State Medical University of the Ministry of Healthcare of Russia. Address: 460014, Orenburg, 6 Sovetskaya St.
E-mail: Veasi73@mail.ru
ORCID: https://orcid.org/0000-0002-2525-0482
Oleg V. Mironchev, MD, PhD (Medicine), associate professor, associate professor of the Department of clinical medicine, Institute of Professional Education of Orenburg State Medical University of the Ministry of Healthcare of Russia. Address: 460014, Orenburg, 6 Sovetskaya St.
E-mail: Olmiron1@rambler.ru


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