Anemia in patients with spondyloarthritis


K.N. Tsaturova, K.D. Dorogoykina, V.I. Machina, A.P. Rebrov

Federal State Budgetary Educational Institution of Hidher Education V.I. Razumovsky Saratov state medical university of the Ministry of Healthcare of Russia, chair of hospital therapy of general medicine Department, Saratov
Objective: to evaluate specifics of anemic syndrome and to determine associations anemia with clinical and laboratory values of the disease. Material and methods. Hemogram, iron metabolism, C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) were evaluated in 110 patients with spondyloarthritis (SpA). Associations between hemoglobin level and BASDAI, ASDAS-CRP, BASFI, laboratory values of systemic inflammatory activity are determined. Results. Anemia was found in 39.1% of patients with SpA, 88.4% of them had mild anemia. Anemia of chronic disease (ACD) and iron deficiency anemia (IDA) was found in 70.3% patients. The inverse relationship between the concentration of hemoglobin and ESR, the level of CRP are revealed. The decrease in hemoglobin level did not depend on the increase of BASDAI and BASFI scores. Conclusion. Anemia is a relevant problem for the patients with SpA. The association between hemoglobin level, ESR, and the level of CRP is a clinical reflection of the pathophysiological mechanisms of the relationship between inflammation and anemia.
Keywords: spondyloarthritis, iron metabolism, anemia of chronic disease, hemoglobin
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    • About the Autors

    Karina N. Tsaturova, attending physician of the chair of hospital therapy of general medicine Department of V.I. Razumovsky Saratov state medical university of the Ministry of Healthcare of Russia. Address: 410012, Saratov, 112 Bolshaya Kazachya Str.. Tel.: +7452491437. E-mail: k.tsaturova@yandex.ru.
    Kseniya D. Dorogoykina, PhD candidate of hospital therapy chair of general medicine Department, V.I. Razumovsky Saratov state medical university of the Ministry of Healthcare of Russia. Address: 410012, Saratov, 112 Bolshaya Kazachya Str.. Tel.: +7452491437. E-mail: axxxinya@mail.ru
    Violetta I. Machina, PhD candidate of hospital therapy chair of general medicine Department, V.I. Razumovsky Saratov state medical university of the Ministry of Healthcare of Russia. Address: 410012, Saratov, 112 Bolshaya Kazachya Str.. Tel.: +7452491437. E-mail: violettamakhina@mail.ru
    Andrey P. Rebrov, MD, professor, head of the chair of hospital therapy of general medicine Department, V.I. Razumovsky Saratov state medical university of the Ministry of Healthcare of Russia. Address: 410012, Saratov, 112 Bolshaya Kazachya Str.. Tel.: +7452491437. E-mail: andreyrebrov@yandex.ru


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