Chronic glomerulonephritis in pregnancy


DOI: https://dx.doi.org/10.18565/therapy.2020.1.78-84

Batyushin M.M.

Rostov State medical University of the Ministry of Healthcare of Russia, Rostov-on-Don
Chronic glomerulonephritis can both precede pregnancy and in this case, as a rule, its diagnosis is not very difficult, and develop during pregnancy. It is also possible to exacerbate the course of nephritis during pregnancy in the last two cases, there are often problems of differential diagnosis with manifestations of nephropathy in pregnant women, preeclampsia and a number of other conditions. The clinical picture of chronic glomerulonephritis can be represented by three main syndromes: urinary, nephritic and nephrotic. In General clinical practice, estimated methods for assessing GFR should be used, in particular, the CKD-EPI formula and the ranking of chronic kidney disease by stages.
Immunosuppressive drugs considered relatively safe in pregnancy include hydroxychloroquine, sulfasalazine, azathioprine and 6-mercaptopurine, as well as colchicine. Glucocorticoids are used during pregnancy. With regard to the feasibility of prolonging pregnancy in chronic glomerulonephritis, it should be noted that there are a number of indications for its termination, which are listed in the article.
Keywords: pregnancy, proteinuria, chronic glomerulonephritis
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About the Autors

Mikhail M. Batyushin, MD, professor, head of the Department of nephrology of the clinic of Rostov State medical University of the Ministry of Healthcare of Russia. Address: 344022, г. Rostov-on-Don, 29 Nakhichevansky Lane.
Tel.: +7 (863) 201-44-23. E-mail: batjushin-m@rambler.ru


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