Modern principles of osteoporosis therapy


DOI: https://dx.doi.org/10.18565/therapy.2021.10.89-93

Zhugrova E.S., Mazurov V.I.

I.I. Mechnikov North-Western state medical university of the Ministry of Healthcare of Russia, Saint Petersburg
Abstract. Osteoporosis is a chronic systemic disease of the skeleton, characterized by low bone mass and deterioration of its quality, which leads to increased fragility of bone tissue. In recent years, due to the understanding of the pathogenesis of the disease, significant therapeutic advances in the treatment of osteoporosis have been made. Despite the availability of many therapeutic medicaments to reduce the risk of fractures, osteoporosis remains a global problem in aging population in many countries, and the burden of osteoporotic fractures remains high, affecting the quality of life of suffering persons. This is connected first of all with comorbidity of osteoporosis and other diseases in senior age groups persons.
Keywords: bone anabolic therapy, antiresorptive therapy, denosumab, comorbidity, bisphosphonates, osteoporosis
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About the Autors

Elena S. Zhugrova, PhD, associate professor of the Department of therapy, rheumatology, examination of temporary disability and quality of medical care named after E.E. Eichwald, I.I. Mechnikov North-West State Medical University of the Ministry of Healthcare of Russia. Address: 191015, Saint Petersburg, 41 Kirochnaya Str. Tel.: +7 (921) 372-80-11. E-mail: jugrova@mail.ru. ORCID: 0000-0002-8622-5205
Вадим Иванович Мазуров, MD, professor, academician of RAS, head of the Department of therapy, rheumatology, examination of temporary disability and quality of medical care named after E.E. Eichwald, I.I. Mechnikov North-West State Medical University of the Ministry of Healthcare of Russia. Address: 191015, Saint Petersburg, 41 Kirochnaya Str. E-mail: maz.nwgmu@yandex.ru. ORCID: 0000-0001-8367-3144


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