Русский
Features of myocardial pathology in patients with extra-axial manifestations of ankylosing spondylitis
DOI: https://dx.doi.org/10.18565/therapy.2022.7.27-32
Feyskhanova L.I., Abdrakipov R.Z., Vivolanets A.A., Akhmedieva D.V., Abdulganieva D.I.
1) Kazan State Medical University of the Ministry of Healthcare of Russia; 2) Republican Clinical Hospital of the Ministry of Healthcare of the Republic of Tatarstan, Kazan
Purpose of the study: to determine the relationship between extra-axial manifestations and cardiac pathology in patients with AS.
Material and methods. A total of 153 patients with AS participated in the study. The patients were divided into 2 groups: 1st – with extraaxial manifestations, 78 people; 2nd gr – without them, 75 people. Patients underwent blood tests to determine the levels of CRP, two-dimensional transthoracic echocardiography, vectorcardiography.
Results. Results of the 1st group: E/A level of transthoracic flow, P loop area were significantly higher; relative thickness of the left ventricular wall inversely correlated with QRS loop area (r=- 0,36, p=0,02); EchoCG and vectorcardiography parameters had no relation with ASDAS-ESR, BASDAI, BASFI indices. Results of the 2nd group: relative wall thickness had a weak direct relationship with ASDAS-ESR index (r=0,29, p=0,03) and an inverse relationship with maximal vector modulus (r=-0,33, p=0,04).
Conclusion. Thus, in AS with extra-axial manifestations, there is an increase in atrial electrical activity accompanied by diastolic dysfunction of the right ventricle.
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About the Autors
Lucia I. Feyskhanova, PhD in Medicine, associate professor of the Department of hospital therapy, Kazan State Medical University of the Ministry of Healthcare of Russia. Address: 420012, Kazan, 49 Butlerova Str. E-mail: ljuts@rambler.ru. ORCID: https://orcid.org/0000-0001-7830-5283
Rifkat Z. Abdrakipov, rheumatologist, head of the Department of rheumatology, Republican Clinical Hospital of the Ministry of Healthcare of the Republic of Tatarstan. Address: 420064 Kazan, 138 Orenburgsky tract. E-mail: hosptherapy@mail.ru. ORCID: https://orcid.org/0000-0003-1140-3238
Anastasia A. Vivolanets, 6th year student of the Faculty of general medicine, Kazan State Medical University of the Ministry of Healthcare of Russia. Address: 420012, Kazan, 49 Butlerova Str. E-mail: vivnastia@gmail.com. ORCID: https://orcid.org/0000-0001-6793-7939
Diana V. Akhmedieva, 6th year student of the Faculty of general medicine, Kazan State Medical University of the Ministry of Healthcare of Russia. Address: 420012, Kazan, 49 Butlerova Str. E-mail: adhimaa@yandex.ru. ORCID: https://orcid.org/0000-0002-7666-0326
Diana I. Abdulganieva, Dr. med. habil., professor, head of the Department of hospital therapy, Kazan State Medical University of the Ministry of Healthcare of Russia. Address: 420012, Kazan, 49 Butlerova Str. E-mail: diana_s@mail.ru. ORCID: https://orcid.org/0000-0001-7069-2725
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