Tubulointersticial nephritis


DOI: https://dx.doi.org/10.18565/therapy.2023.3.114-120

Batyushin M.M., Zakusilov D.I., Sigitova O.N.

1) Rostov State Medical University of the Ministry of Healthcare of Russia, Rostov-on-Don; 2) Kazan State Medical University of the Ministry of Healthcare of Russia; 3) Kazan State Medical Academy – a branch of Russian Medical Academy of Continuous Professional Education of the Ministry of Healthcare of Russia
Abstract. Chronic tubulointerstitial nephritis (CTIN) is a chronic kidney disease that develops in response to long-term exposure to exogenous and /or endogenous factors and is manifested by inflammatory changes in tubulointerstitial tissue with the formation of interstitial fibrosis and tubular atrophy accompanied by frequent development of chronic kidney disease. In clinical practice, TIN often occurs as an acquired form, mainly due to medicamentous exposure or infectious inflammation of renal tissue (pyelonephritis). The article contains issues related to the etiology, pathogenesis, clinic and diagnosis of CTIN. Approaches to the treatment of CTIN patients are given, taking into account their individual etiopathogenetic characteristics. The article has a form of a brief abstract on STIN problem for primary care physician help.
Keywords: tubulointerstitial kidney disease, chronic tubulointerstitial nephritis, chronic kidney disease
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About the Autors

Mikhail M. Batyushin, MD, professor, professor of the Department of internal medicine No. 2, Rostov State Medical University of the Ministry of Healthcare of Russia, Address: 344000, Rostov-on-Don, 29 Nakhichevansky Lane. E-mail: batjushin-m@rambler.ru. ORCID: https://orcid.org/0000-0002-5329-7050
Dmitry I. Zakusilov, assistant at the Department of medical rehabilitation, sports medicine, physical education with a course of medical and social expertise, Rostov State Medical University of the Ministry of Healthcare of Russia, Address: 344000, Rostov-on-Don, 29 Nakhichevansky Lane. ORCID: https://orcid.org/0000-0002-6455-9204
Olga N. Sigitova, MD, professor of the Department of polyclinic therapy and general medical practice, Kazan State Medical University of the Ministry of Healthcare of Russia, professor of the Department of urology of Kazan
State Medical Academy – a branch of Russian Medical Academy of Continuous Professional Education of the Ministry of Healthcare of Russia. Address: 420012, Kazan, 49 Butlerova Str. E-mail: osigit@rambler.ru. ORCID: https://orcid.org/0000-0001-8983-245X


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