Impact of long-term antiarrhythmic therapy on the progression of atrial fibrillation from paroxysmal to permanent form


DOI: https://dx.doi.org/10.18565/therapy.2023.7.208-213

Tarzimanova A.I.

I.M. Sechenov First Moscow State Medical University of the Ministry of Healthcare of Russia (Sechenov University)
Abstract. In recent years, it has been proven that there is a certain pattern in the long-term course of atrial fibrillation (AF): from asymptomatic, short episodes of arrhythmia to a stable permanent form of the disease, which creates the prerequisites for the progression of chronic heart failure and significantly worsens the prognosis for patients. The duration of the existence of paroxysmal or persistent form of AF in different patients can vary in a wide range – from several months to decades
– and is interconnected with the severity of underlying disease. Paroxysmal AF persists for many years in only a small part of patients. Slowing the progression of AF from paroxysmal to permanent form improves the prognosis of patients, therefore, the assessment of risk factors for the progression of arrhythmia and prescription the correct tactics for managing patients are urgent tasks of modern cardiology.

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About the Autors


Aida I. Tarzimanova, MD, professor of the Department of faculty therapy No. 2, I.M. Sechenov First Moscow State Medical University of the Ministry of Healthcare of Russia (Sechenov University). Address: 119048, Moscow, 24 Efremova Str.
E-mail: tarzimanova@mail.ru
ORCID: https://orcid.org/0000-0001-9536-8307


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