Русский
Correction of electrical instability of the myocardium at recurrent tonsillitis
DOI: https://dx.doi.org/10.18565/therapy.2023.8.8-13
Zorkina A.V., Sipyagina M.K., Zorkin M.V., Skopina Yu.A.
1) N.P. Ogarev National Research Mordovia State University, Saransk; 2) Federal Scientific and Clinical Center of FMBA of Russia, Moscow
The objective of the work is to assess the parameters of bioelectrical activity of the myocardium in patients with recurrent tonsillitis against the background of the introduction of ethylmethylhydroxypyridine succinate into complex therapy.
Material and methods. All patients were undergoing inpatient treatment in the infectious diseases hospital. ECG was recorded upon admission and discharge of patients. Patients were divided into two groups. Group 1 received standard basic therapy, group 2 was additionally prescribed ethylmethylhydroxypyridine succinate 5% 4,0 ml IV drip No. 5. The average, minimum, maximum duration of the P wave, PQ, QT intervals were assessed. The duration of QT, corrected by heart rate (QTc), dispersion of indicators DР, DРQ, DQT, DQTс were calculated. The results obtained were assessed depending on the preserved or reduced ejection fraction (EF) according to echocardioscopy.
Results and conclusion. Upon admission, the indicators QTc, DP, DPQ, DQT, DQTc exceeded those of healthy volunteers. By the time of discharge, in patients of group 1, the studied indicators remained at the same high level (with EF <55%) or even significantly increased (with EF >55%), despite the treatment. This proved the preservation of arrhythmogenic readiness of the myocardium. In patients of group 2, there was a decrease in indicators and achievement of the level of healthy volunteers, including patients with an initially reduced ejection fraction.
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About the Autors
Angelina V. Zorkina, MD, professor, professor of the Department of outpatient therapy, N.P. Ogarev National Research Mordovia State University. Address: 430032, Saransk, 26а Ulyanova St.
E-mail: wind-lina@mail.ru
ORCID: https://orcid.org/0000-0003-1122-9532
Maria K. Sipyagina, PhD in Medical Sciences, functional diagnostics doctor at Federal Scientific and Clinical Center of FMBA of Russia. Address: 115682, Moscow, 28 Orekhovy Boulevard.
E-mail: Sipjaginy@mail.ru
ORCID: https://orcid.org/0009-0000-2530-552Х
Mikhail V. Zorkin, PhD in Medical Sciences, associate professor of the Department of outpatient therapy, N.P. Ogarev National Research Mordovia State University. Address: 430032, Saransk, 26а Ulyanova St.
E-mail: saerdan@mail.ru
ORCID: https://orcid.org/0000-0002-1862-6613.
Yulia A. Skopina, PhD in Medical Sciences, associate professor of the Department of outpatient therapy, N.P. Ogarev National Research Mordovia State University. Address: 430032, Saransk, 26а Ulyanova St.
E-mail: skopina@bk.ru
ORCID: https://orcid.org/0000-0001-7598-5690
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