Influence of vibro-hazardous production at the clinical course of diabetes mellitus type 2


DOI: https://dx.doi.org/10.18565/therapy.2025.1.103-107

Oleinik V.S., Davydova E.V.

South Ural State Medical University of the Ministry of Healthcare of Russia, Chelyabinsk
Abstract. Comorbidity is of key importance in the course of diabetes mellitus type 2 (T2DM). The impact of long-term exposure to industrial vibration on male individuals with T2DM and complications provoked by this exogenous factor are considered in the article.
The aim: to study the peculiarities of carbohydrate, lipid metabolism, testosterone levels and cardiorenal risks in case of T2DM in patients who are long-susceptible for production vibration.
Material and methods. From 2022 to 2024, 1606 male patients were examined for DM 2. Two groups were compared: in the 1st (T2DM, n = 112), were included patients, who never had a contact with harmful production factors, in the 2nd (T2DM and vibration disease, DMBD, n = 138) – patients who have been exposed to industrial vibration for a long time, on average for 21 [15; 31] year. There were no significant differences in age in patients from the 1st and 2nd groups: 57 [51; 63] and 59 [49.3; 64.0] years, respectively (p = 0.537).
Results and discussion. According to the results of diagnosis, statistically significant differences between the comparison groups were identified in terms of glycated hemoglobin, total cholesterol, high density lipoproteins, triglycerides, total testosterone, sex hormone binding globulin, creatinine. In DMBD group, reliable deviations of the abovementioned biomarkers were noted, while the patients of both groups had a history of arterial hypertension disease. On the body mass index, age and duration of T2DM, there were no statically significant intergroup differences. Thus, in case of T2DM contact with production vibration provokes a cascade of pathogenetic processes.
Conclusion. In patients with T2DM who have been exposed to industrial vibration for a long time, there are reliably worse indicators of glycemic, lipid, androgenic status, hypertension.
Keywords: vibro-hazardous production facilities, cardiorenal continuum, testosterone, endothelial dysfunction, diabetes mellitus, risk factors
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About the Autors

Vitaly S. Oleinik, MD, assistant at the Department of faculty therapy, South Ural State Medical University of the Ministry of Healthcare of Russia. Address: 454092, Chelyabinsk, 64 Vorovskogo St.
E-mail: vitaly060894@mail.ru
ORCID: https://orcid.org/0009-0002-0073-5798
Evgeniya V. Davydova, MD, Dr. Sci. (Medicine), professor, professor of the Department of faculty therapy, South Ural State Medical University of the Ministry of Healthcare of Russia. Address: 454092, Chelyabinsk, 64 Vorovskogo St.
E-mail: davidovaevchel@yandex.ru
ORCID: https://orcid.org/0000-0003-4432-2477


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