Pulmonary artery thromboembolism (PATE) is an actual problem for clinicians due to its high prevalence (100 per 100 000 population) and high mortality. It is especially difficult to diagnose and treat patients with pulmonary embolism in combination with acute myocardial infarction (AMI). The article presents the case of a 69-year-old male patient who was urgently taken from the district hospital after the performed thrombolysis with purolase to the vascular center of the regional clinical hospital with a diagnosis: ishemic heart disease: acute apical-lateral Q myocardial infarction, KillipI; atrial fibrillation. The patient complained of chest pain, shortness of breath and weakness, never had ishemic heart disease, had a history of arterial hypertension and COPD, and had abused alcohol in the last 5 years in doses of at least 400 ml of strong alcoholic beverages 4–5 times a week. The diagnosis of myocardial infarction was confirmed during coronary angiography. Along with this, recurrent pulmonary embolism was detected on the phone of hepatic cirrhosis of the liver, cholangiocellular carcinoma, which led to the death of the patient. This clinical observation confirms the high risk of pulmonary embolism in case of comorbid pathology. This requires clarification of the methods of antithrombotic therapy, taking into account the risk of repeated thrombotic and hemorrhagic complications.

Keywords: pulmonary thromboembolism, comorbid pathology, myocardial infarction