Ways to optimize the prediction of fatal and non-fatal cases of stroke in patients with peripheral atherosclerosis


DOI: https://dx.doi.org/10.18565/therapy.2022.1.21-27

Kobzeva N.D., Martynov A.I., Terentiev V.P.

1) Rostov State Medical University of the Ministry of Healthcare of Russia, Rostov-on-Don; 2) A.I. Yevdokimov Moscow State University of Medicine and Dentistry of the Ministry of Healthcare of Russia
Abstract. Recently, there has been a significant increase in interest in research aimed at predicting cardiovascular risk in individuals with peripheral atherosclerosis.
Aim: to study the effect of atherosclerotic lesions of various vascular basins on long-term prognosis and optimization of prediction of fatal and non-fatal cases of stroke in patients with peripheral atherosclerosis.
Material and methods. The study included 519 patients with lesions of various vascular basins, who were treated in specialized departments. The average age of the examined patients was 60.0±8.7 years.
Results. In the course of two-factor logistic regression analysis, we obtained a complex of factors that influence the risk of developing nonfatal cases of stroke, namely, «chronic ischemia of the lower limb + abdominal aorta» (p=0.043), «amputation of the lower limb in history + chronic ischemia of the lower limbs» (p=0.017).
Conclusions. Original nomograms have been developed to assess the risk of stroke in patients with peripheral atherosclerosis.
Keywords: fatal and nonfatal stroke, prospective observation, peripheral atherosclerosis, long-term prognosis
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About the Autors

Natalia D. Kobzeva, PhD, assistant at the Department of internal diseases No. 1, Rostov State Medical University of the Ministry of Healthcare of Russia. Address: 344022, Rostov-on-Don, 29 Nakhichevansky Lane.
E-mail: kobzeva.nataliya1@gmail.com. ORCID: https://orcid.org/ 0000-0002-3390-2452
Anatoly I. Martynov, MD, academician of RAS, professor of the Department of hospital therapy No. 1, A.I. Yevdokimov Moscow State University of Medicine and Dentistry of the Ministry of Healthcare of Russia. Address: 127473, Moscow, 20/1 Delegatskaya Str. ORCID: https://orcid.org/ 0000-0002-0783-488X
Vladimir P. Terentiev, MD, professor, head of the Department of internal diseases No. 1, Rostov State Medical University of the Ministry of Healthcare of Russia. Address: 344022, Rostov-on-Don, 29 Nakhichevansky Lane.
E-mail: vpterentev@mail.ru. ORCID: https://orcid.org/ 0000-0003-3607-5832


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