Cerebral venous discirculation in patients with chronic obstructive pulmonary disease in acute stage


DOI: https://dx.doi.org/10.18565/therapy.2022.9.7-12

Sargsyan K.A., Stulin I.D. , Musin R.S., Malyavin A.G., Trukhanov S.A., Bekoeva Z.R., Seleznev F.A.

1) A.I. Yevdokimov Moscow State University of Medicine and Dentistry of the Ministry of Healthcare of Russia; 2) Centrosoyuz Hospital of the Russian Federation, Moscow; 3) Moscow Multidisciplinary Clinical Center «Kommunarka» of the Department of Healthcare of Moscow
Abstract. Systemic venous dyscirculation frequently accompanies chronic obstructive pulmonary disease (COPD). There is evidence of its significant contribution to encephalopathy, but the degree of venous outflow disturbances and their association with clinical symptoms have been insufficiently studied.
Purpose: clinical and instrumental assessment of the presence and severity of cerebral venous dyscirculation in patients with COPD in the acute stage.
Material and methods. 100 patients with mild and severe chronic obstructive pulmonary disease were investigated in the stage of aggravation. The comparison group included 50 patients with the confirmed absence of respiratory disorders. Complaints, neurological examination, assessment of external respiration function, cardiorespiratory monitoring, duplex scanning were performed.
Results. Significant increase of maximal flow velocities along the vertebral plexuses and orbital veins were revealed in COPD patients, as well as reliable strong correlations with the volume of FEV1. Among the complaints associated with venous dyscirculation was daytime sleepiness and possibly difficulty waking up.
Conclusion. The presence of cerebral venous dyscirculation in the early stages of COPD development and its association with some complaints of patients is confirmed.

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About the Autors


Kristina A. Sargsyan, head of the Department of neurology, Centrosoyuz Hospital of the Russian Federation. Address: 107150, Moscow, 39/1 Losinoostrovskaya Str. E-mail: kriny07@mail.ru.
ORCID: https://orcid.org/0000-0003-3628-2161
Igor D. Stulin , Dr. med. habil., professor, until 2021 – head of the Department of nervous diseases of the Faculty of general medicine, A.I. Yevdokimov Moscow State University of Medicine and Dentistry of the Ministry of Healthcare of Russia. ORCID: https://orcid.org/0000-0002-8683-2806
Rashit S. Musin, Dr. med. habil., professor of the Department of nervous diseases of the Faculty of general medicine, A.I. Yevdokimov Moscow State University of Medicine and Dentistry of the Ministry of Healthcare of Russia. Address: 127473, Moscow, 20/1 Delegatskaya Str. E-mail: rashel.63@mail.ru.
ORCID: https://orcid.org/0000-0001-9205-6658
Andrey G. Malyavin, Dr. med. habil., professor of the Department of phthisiology and pulmonology of the Faculty of general medicine, A.I. Yevdokimov Moscow State University of Medicine and Dentistry of the Ministry of Healthcare of Russia. Address: 127473, Moscow, 20/1 Delegatskaya Str. E-mail: maliavin@mail.ru. ORCID: https://orcid.org/000-0002-6128-5914
Sergei A. Trukhanov, PhD in Medicine, associate professor of the Department of nervous diseases of the Faculty of general medicine, A.I. Yevdokimov Moscow State University of Medicine and Dentistry of the Ministry of Healthcare of Russia. Address: 127473, Moscow, 20/1 Delegatskaya Str. E-mail: severyaninpage@mail.ru. ORCID: https://orcid.org/0000-0003-2071-6359
Zemfira R. Bekoeva, head of Neurological Department for patients with acute disorders of cerebral circulation, Moscow Multidisciplinary Clinical Center «Kommunarka» of the Department of Healthcare of Moscow. Address: 108814, Moscow, 8 Sosensky stan Str. E-mail: bekoevaz@mail.ru
Fedor A. Seleznev, PhD in Medicine, assistant at the Department of nervous diseases of the Faculty of general medicine, A.I. Yevdokimov Moscow State University of Medicine and Dentistry of the Ministry of Healthcare of Russia. Address: 127473, Moscow, 20/1 Delegatskaya Str. E-mail: seleznevfa@gmail.com.
ORCID: https://orcid.org/0000-0001-7941-7682


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