Русский
Hyperammoniemia: New aspects of etiopathogenesis
DOI: https://dx.doi.org/10.18565/therapy.2023.8.95-96
Pan A.A., Zaykova-Khelimskaya I.V., Alekseenko S.A.
Far Eastern State Medical University of the Ministry of Healthcare of Russia, Khabarovs=k
Literature
1. Лекции по белкам. Биохимия. ТГМУ. 2005; с. 13. [Lectures on proteins. Biochemistry. Pacific State Medical University. 2005; p. 13 (In Russ.)]. 2. Лазебник Л.Б., Голованова Е.В., Алексеенко С.А. с соавт. Российский консенсус «Гипераммониемии у взрослых» (версия 2021). Экспериментальная и клиническая гастроэнтерология. 2021; (3): 97–118. [Lazebnik L.B., Golovanova E.V., Alekseenko S.A. et al. Russian consensus «Hyperammonemia in adults» (version 2021). Eksperimental’naya i klinicheskaya gastroenterologiya = Experimental and Clinical Gastroenterology. 2021; (3): 97–118 (In Russ.)]. https://dx.doi.org/10.31146/1682-8658-ecg-187-3-97-118. EDN: IXZDGZ. 3. Алексеенко С.А., Агеева Е.А., Полковникова О.П. Современные подходы к диагностике и лечению гипераммониемии у пациентов с хроническими заболеваниями печени на доцирротической стадии. РМЖ. Медицинское обозрение. 2018; 2(7–1): 19–23. [Alekseenko S.A., Ageeva E.A., Polkovnikova O.P. Modern approaches to the diagnosis and treatment of hyperammonemia in patients with chronic liver diseases at the pre-cirrhotic stage. Russkiy meditsinskiy zhurnal. Meditsinskoye obozreniye = Russian Medical Journal. Medical Review. 2018; 2(7–1): 19–23 (In Russ.)]. EDN: YAUTVB. 4. Wang Q., Guan K., Lv Y. et al. Disturbance of hepatocyte growth and metabolism in a hyperammonemia microenvironment. Arch Biochem Biophys. 2022; 716: 109109. https://dx.doi.org/10.1016/j.abb.2021.109109. 5. Wang Q., Wang Y., Yu Z. et al. Ammonia-induced energy disorders interfere with bilirubin metabolism in hepatocytes. Arch Biochem Biophys. 2014; 555–556: 16–22. https://dx.doi.org/10.1016/j.abb.2014.05.019. 6. Косенко Е.А., Тихонова Л.А., Алилова Г.А. с соавт. Портокавальное шунтирование вызывает дифференциальную выработку митохондриального супероксида в областях мозга. Свободнорадикальная биология и медицина. 2017; с. 109–118. [Kosenko E.A., Tikhonova L.A., Alilova G.A. et al. Portacaval shunting causes differential mitochondrial superoxide production in brain regions. Free Radical Biology and Medicine. 2017; pp. 109–118 (In Russ.)]. 7. Felipo V., Butterworth R.F. Neurobiology of ammonia. Prog Neurobiol. 2002; 67(4): 259–79. https://dx.doi.org/10.1016/s0301-0082(02)00019-9. 8. Adlimoghaddam A., Sabbir M.G., Albensi B.C. Ammonia as a potential neurotoxic factor in Alzheimer’s disease. Front Mol Neurosci. 2016; 9: 57. https://dx.doi.org/10.3389/fnmol.2016.00057. 9. Cabrera-Pastor A., Arenas Y.M., Taoro-Gonzalez L. et al. Chronic hyperammonemia alters extracellular glutamate, glutamine and GABA and membrane expression of their transporters in rat cerebellum. Modulation by extracellular cGMP. Neuropharmacology. 2019; 161: 107496. https://dx.doi.org/10.1016/j.neuropharm.2019.01.011. 10. Голованова Е.В. Аммиак – актуальная проблема врача и пациента в терапевтической практике. Терапия. 2018; 4(2): 49–55. [Golovanova E.V. Ammonia is an actual problem of a doctor and a patient in therapeutic practice. Terapiya = Therapy. 2018; 4(2): 49–55 (In Russ.)]. EDN: YUDWVO. 11. Галеева З.М., Галиуллин О.Ф., Езюкова Е.Г., Тухбатуллина Р.Г. Гипераммониемия в клинической практике: анализ собственных клинических наблюдений. Медицинский алфавит. 2019; 4(38): 23–26. [Galeeva Z.M., Galiullin O.F., Ezyukova E.G., Tukhbatullina R.G. Hyperammonemia in clinical practice: analysis of own clinical observations. Meditsinskiy alfavit = Medical Alphabet. 2019; 4(38): 23–26 (In Russ.)]. https://dx.doi.org/10.33667/2078-5631-2019-4-38(413)-23-26. EDN: HPXAZR. 12. Плотникова Е.Ю., Синькова М.Н., Исаков Л.К. Астения и утомление при гипераммониемии: этиопатогенез и методы коррекции. Медицинский совет. 2021; (21–1): 95–104. [Plotnikova E.Yu., Sinkova M.N., Isakov L.K. Asthenia and fatigue in hyperammonemia: etiopathogenesis and methods of correction. Meditsinskiy sovet = Medical Council. 2021; (21–1): 95–104 (In Russ.)]. https://dx.doi.org/10.21518/2079-701X-2021-21-1-95-104. EDN: XLILJK. 13. Долгушина А.И., Кузнецова А.С., Картошкина Ю.В., Селянина А.А. Усталость и уровень аммиака капиллярной крови у студентов медицинского университета. Экспериментальная и клиническая гастроэнтерология. 2020; (4): 31–32. [Dolgushina A.I., Kuznetsova A.S., Kartoshkina Yu.V., Selyanina A.A. Fatigue and capillary blood ammonia levels in medical university students. Eksperimental’naya i klinicheskaya gastroenterologiya = Experimental and Clinical Gastroenterology. 2020; (4): 31–32 (In Russ.)]. https://dx.doi.org/10.31146/1682-8658-ecg-176-4-31-38. EDN: APNJIQ. 14. Granados-Fuentes D., Cho K., Patti G.J. et al. Hyperammonaemia disrupts daily rhythms reversibly by elevating glutamate in the central circadian pacemaker. Liver Int. 2023; 43(3): 673–83. https://dx.doi.org/10.1111/liv.15476. 15. Lin F.P., Ferrando A.A., Dennis R.A. et al. Exercise induced hyperammonemia does not precipitate overt hepatic encephalopathy. Hepatology. 2020; 72(2): 778–80. https://dx.doi.org/10.1002/hep.31148. 16. Кожевникова С.А., Трибунцева Л.В., Будневский А.В. Гипераммониемия у пациентов с хронической обструктивной болезнью легких и ожирением: механизмы ассоциации, частота выявления и возможности коррекции. Терапевтический архив. 2020; 92(2): 55–60. [Kozhevnikova S.A., Tribuntseva L.V., Budnevsky A.V. Hyperammonemia in patients with chronic obstructive pulmonary disease and obesity: Mechanisms of association, frequency of detection and possibilities for correction. Terapevticheskiy arkhiv = Therapeutic Archive. 2020; 92(2): 55–60 (In Russ.)]. https://dx.doi.org/10.26442/00403660.2020.02.000562. EDN: GXFIUM. 17. Плотникова Е.Ю., Воросова О.А., Баранова Е.Н. с соавт. Работа в ночную смену и гипераммониемия у врачей. РМЖ. 2021; 29(4): 49–52. [Plotnikova E.Yu., Vorosova O.A., Baranova E.N. Night work and hyperammonemia in doctors. Russkiy meditsinskiy zhurnal = Russian Medical Journal. 2021; 29(4): 49–52 (In Russ.)]. EDN: MEFOYY. 18. Nakai M., Suda G., Ogawa K. et al. Efficacy of rifaximin against covert hepatic encephalopathy and hyperammonemia in Japanese patients. PLoS One. 2022; 17(7): e0270786. https://dx.doi.org/10.1371/journal.pone.0270786. 19. Groeneweg M., Moerland W., Quero J.C. et al. Screening of subclinical hepatic encephalopathy. J Hepatol. 2000; 32(5): 748–53. https://dx.doi.org/10.1016/s0168-8278(00)80243-3. 20. Schomerus H., Hamster W. Quality of life in cirrhotics with minimal hepatic encephalopathy. Metab Brain Dis. 2001; 16(1–2): 37–41. https://dx.doi.org/10.1023/a:1011610427843. 21. Bajaj J.S., Hafeezullah M., Hoffmann R.G., Saeian K. Minimal hepatic encephalopathy: A vehicle for accidents and traffic violations. Am J Gastroenterol. 2007; 102(9): 1903–9. https://dx.doi.org/10.1111/j.1572-0241.2007.01424.x. 22. Singh J., Sharma B.C., Puri V. et al. Sleep disturbances in patients of liver cirrhosis with minimal hepatic encephalopathy before and after lactulose therapy. Metab Brain Dis. 2017; 32(2): 595–605. https://dx.doi.org/10.1007/s11011-016-9944-5.
About the Autors
Anastasia A. Pan, cardiologist at Clinical Hospital «RZD-Medicine». Address: 680022, Khabarovsk, 49 Voronezhskaya St.
E-mail: gjpbbnbdd@mail.ru
ORCID: https://orcid.org/0009-0006-1606-5919
Irina V. Zaykova-Khelimskaya, MD, professor, employee of the Department of hospital therapy, Far Eastern State Medical University of the Ministry of Healthcare of Russia. Address: 680000, Khabarovsk, 35 Karla Marksa St.
E-mail: irinavh@mail.ru
ORCID: https://orcid.org/0000-0002-7517-4027
Sergey A. Alexeenko, MD, professor, head of the Department of hospital therapy, Far Eastern State Medical University of the Ministry of Healthcare of Russia. Address: 680000, Khabarovsk, 35 Karla Marksa St.
E-mail: sa.alexeenko@gmail.com
ORCID: https://orcid.org/0000-0003-1724-9980
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