Dufficult-to-treat psoriatic arthritis in a young patient with metabolic syndrome


DOI: https://dx.doi.org/10.18565/therapy.2024.10.120-124

Denisenko A.S., Gasanov M.Z., Chulkov V.S., Abdieva K.I., Azovtseva O.V.

1) Yaroslav the Wise Novgorod State University, Veliky Novgorod; 2) Novgorod Regional Clinical Hospital, Veliky Novgorod
Abstract. Psoriatic arthritis (PsA) attracts the attention of researchers and practitioners for many reasons, including such associated problems as high comorbidity and cases of failure to achieve treatment goals despite adequate therapy. Current article presents a clinical example of dufficult-to-treat PsA in a young patient having signs of metabolic syndrome (MS). Currently, he is becoming therapy with the sixth genetically engineered biological drug (the first was prescribed in 2013), and for a long period of time he cannot achieve satisfactory control over his body weight. It could be assumed that obesity and MS make a significant contribution to the impossibility of achieving stable remission of PsA. Probably, the implementation of dufficult-to-treat PsA criteria into clinical practice in combination with the use of an interdisciplinary approach to the management of such kind of patients will improve the efficacy of treatment regimens, prognosis and life quality of patients with that disease.
Keywords: dufficult-to-treat psoriatic arthritis, genetically engineered biological therapy, psoriasis, metabolic syndrome, obesity
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About the Autors

Anastasia S. Denisenko, MD, assistant professor of the Department of general pathology of the Institute of medical education, Yaroslav the Wise Novgorod State University. Address: 173020, Veliky Novgorod, 6 Derzhavina St.
E-mail: dsstasy-98@yandex.ru
ORCID: https://orcid.org/0000-0003-4663-4730
Mitkhat Z. Gasanov, MD, PhD (Medicine), deputy director of the Institute of medical education, Yaroslav the Wise Novgorod State University, associate professor of the Department of internal medicine. Address: 173020, Veliky Novgorod, 6 Derzhavina St.
E-mail: mitkhat.gasanov@novsu.ru
ORCID: https://orcid.org/0000-0001-5856-0404
Vasily S. Chulkov, MD, Dr. Sci. (Medicine), director of the Institute of medical education, Yaroslav the Wise Novgorod State University, professor of the Department of internal medicine. Address: 173020, Veliky Novgorod, 6 Derzhavina St.
E-mail: vschulkov@rambler.ru
ORCID: https://orcid.org/0000-0002-0952-6856
Kristina I. Abdieva, MD, rheumatologist at Novgorod Regional Clinical Hospital. Address: 173008, Veliky Novgorod, 14 Pavla Levitta St.
E-mail: kristina.abdieva@mail.ru
Olga V. Azovtseva, MD, Dr. Sci. (Medicine), head of the Department of microbiology, immunology and infectious diseases of the Institute of medical education, Yaroslav the Wise Novgorod State University. Address: 173020, Veliky Novgorod, 6 Derzhavina St.
E-mail: olga.azovtseva@novsu.ru
ORCID: https://orcid.org/0000-0002-5548-7819


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