A modern approach to the treatment of heart failure in a patient with heart amyloidosis by valsartan/sakubitril combination


DOI: https://dx.doi.org/10.18565/therapy.2019.6.171-175

Koltsov A.V., Kalimulin O.A., Tyrenko V.V., Gretskaya E.V., Bologov S.G., Sinopalnikov D.O.

S.M. Kirov Military medical Academy of the Ministry of Defense of the Russian Federation
Heart failure is the main syndrome leading to an increase in mortality rate among patients with pathology of blood circulatory system. Currently, the most common cause of heart failure in adults is undoubtedly considered to be coronary heart disease (CHD). Then are following arterial hypertension, diabetes mellitus, atrial fibrillation and heart defects. However, there are exclusive cases, such as cardiac amyloidosis, which require more informative coverage among practitioners. The article presents a case of cardiac amyloidos in an elderly patient. On the background of the ongoing therapy with valsartan/sakubitrile combination, a significant positive dynamics was observed in the form of smoothing the manifestations of heart failure decompensation, improvement of the left ventricle contractility, and a stable course of the disease without signs of progression during the observation period. The patient continues to be under dynamic observation. Thus, we can talk about the effective treatment of chronic heart failure in a patient with primary cardiac amyloidosis by means of valsartan/sakubitrile combination.
Keywords: valsartan / sacubitrile, cardiac amyloidosis, heart failure
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About the Autors

Andrei V. Koltsov, PhD, head of the Department of the clinic for faculty therapy of S.M. Kirov Military medical Academy of the Ministry of Defense of the Russian Federation. Address: 194044, St. Petersburg, 6 Academika Lebedeva Str. Tel.: +7 (812) 542-82-48. Email: Andrewkoltsov83@gmail.com
Oleg A. Kalimulin, adjunct of the Department of faculty therapy of S.M. Kirov Military medical Academy of the Ministry of Defense of the Russian Federation. Address: 194044, St. Petersburg, 6 Academika Lebedeva Str. Tel.: +7 (812) 542-82-48. E-mail: Olegin-83@mail.ru
Vadim V. Tyrenko, MD, professor, head of the department/clinic of faculty therapy of S.M. Kirov Military medical Academy of the Ministry of Defense of the Russian Federation. Address: 194044, St. Petersburg, 6 Academika Lebedeva Str. Tel.: +7 (812) 542-82-48. E-mail: vadim_tyrenko@mail.ru
Ekaterina V. Gretskaya, head of the cabinet of echocardiography of the Department of functional diagnostics of faculty therapy clinic of S.M. Kirov Military medical Academy of the Ministry of Defense of the Russian Federation. Address: 194044, St. Petersburg, 6 Academika Lebedeva Str. Tel.: +7 (812) 542-82-48. E-mail: Gev306@yandex.ru
Sergey G. Bologov, MD, professor of the Department of faculty therapy of S.M. Kirov Military medical Academy of the Ministry of Defense of the Russian Federation. Address: 194044, St. Petersburg, 6 Academika Lebedeva Str. Tel.: +7 (812) 542-82-48. E-mail: bologovs@inbox.ru
Dmitry O. Sinopalnikov, PhD, associate professor of the Department of faculty therapy of S S.M. Kirov Military medical Academy of the Ministry of Defense of the Russian Federation. Address: 194044, St. Petersburg, 6 Academika Lebedeva Str. Tel.: +7 (812) 542-82-48. Email: sinop.dmitriy63@gmail.com


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