Influence of dietary fiber on metabolism of gut microbiota and carbohydrate metabolism


DOI: https://dx.doi.org/10.18565/therapy.2022.8.107-113

Demidova T.Yu., Korotkova T.N., Kochina A.S.

1) N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia, Moscow; 2) Federal Research Center for Nutrition and Biotechnology, Moscow
Abstract. Currently, more and more research works are devoted to dietary fiber (DF) and its effect on the body of healthy people and patients with various diseases. The effectiveness of DF has been shown not only in terms of correcting existing disorders, but also in preventing such diseases as, for example, type 2 diabetes mellitus, one of the pathogenetic factors of which is an intestinal microbiota imbalance. DFs are known to serve as an energy substrate for the intestinal microbiota and as a factor regulating its metabolism. However, due to the poor tolerability of DFs by many patients, recommendations for their use are not adequately implemented as it should be. In addition, some sources of DF are difficult to access or do not meet the financial capabilities of the population. Performing studies on the influence of this group of substances at carbohydrate metabolism can help create more accurate recommendations concerning amount and type of DF used in a given situation, as well as increase the patients’ interest in their use.
Keywords: short-chain fatty acids, dietary fiber, intestinal microbiota, diabetes mellitus, obesity
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About the Autors

Tatyana Yu. Demidova, Dr. med. habil., professor, head of the Department of endocrinology of the Faculty of general medicine, N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia. Address: 117321, Moscow, 1 Ostrovityanova Str. E-mail: t.y.demidova@gmail.com. ORCID: https://orcid.org/0000-0001-6385-540X
Tatyana N. Korotkova, PhD in Medicine, head of the Laboratory of clinical biochemistry, allergology and immunology, Federal Research Center for Nutrition and Biotechnology. Address: 109240, Moscow, 2/14 Ustyinsky Drive. E-mail: tntisha@gmail.com. ORCID: https://orcid.org/0000-0002-3684-9992
Anna S. Kochina, postgraduate student of the Department of endocrinology of the Faculty of general medicine, N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia. Address: 117321, Moscow, 1 Ostrovityanova Str. E-mail: anna_kochina_@mail.ru. ORCID: https://orcid.org/0000-0002-6826-5924


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