Stress and its influence at the cardiovascular system


DOI: https://dx.doi.org/10.18565/therapy.2022.9.118-128

Belyaeva I.A., Pyokhova Ya.G., Vershinin A.A.

1) N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia, Moscow; 2) National Medical Research Center for Rehabilitation and Balneology of the Ministry of Healthcare of Russia, Moscow
Abstract. A modern view on the role of physical and psychosocial stress in the development of cardiovascular diseases (CVD) is highlighted in the review. The review presents stress research directions and application of their results in clinical practice, current knowledge about the transformation of brain architectonics, cardiovascular system, and the correlation with clinical symptoms of CVD. The search depth of publications was 10 years, from 2011 to 2021, and a number of earlier, fundamental works on stress subject area were also included in the review. For the selection of publications, the PubMed, MEDLINE, Cochrane Library databases were studied, were selected the studies that meet the requirements of the class and level of evidence IA and IB, IIA (randomized clinical trials, meta-analyses, systematic reviews).
Keywords: heart attack, brain stroke, amygdala, prefrontal cortex, hypothalamic-pituitary-adrenal axis, psychosocial stress, physical stress, cortisol, adrenaline, depression, anxiety, treatment, hippocampus
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About the Autors

Irina A. Belyaeva, Dr. med. habil., professor, professor of the Department of neurology, neurosurgery and medical genetics, N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia, chief researcher at the Department of neurorehabilitation and clinical psychology, National Medical Research Center for Rehabilitation and Balneology of the Ministry of Healthcare of Russia. Address: 119415, Moscow, 42/6 Lobachevskogo Str. E-mail: m-martin@inbox.ru. ORCID: https://orcid.org/0000-0002-2071-3345
Yana G. Pyokhova, researcher at the Department of neurorehabilitation and clinical psychology, National Medical Research Center for Rehabilitation and Balneology of the Ministry of Healthcare of Russia. Address: 121099, Moscow, 32 Novy Arbat Str. E-mail: PehovaYG@nmicrk.ru. ORCID: https://orcid.org/0000-0002-2754-1021
Aleksey A. Vershinin, cardiologist, functional diagnostics doctor at National Medical Research Center for Rehabilitation and Balneology of the Ministry of Healthcare of Russia. Address: 121099, Moscow, 32 Novy Arbat Str. E-mail: VershininAA@nmicrk.ru


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